Active Folate 1000

Biologically active folate rich formula*
• Promotes healthy homocysteine levels*
• Provides 1000 mcg of folate per day from Metafolin®

Active Folate 1000 provides 1000 mcg of folate per day from Metafolin® in its physiologically active form.1* Folate is primarily involved in DNA synthesis and methylation reactions, including the conversion of homocysteine to methionine.2 Supplementation has been shown to be the most effective method for raising folate status, yielding superior results to dietary intake.3* Metafolin® is a proprietary and bioavailable form of the folate found naturally in foods that does not mask a vitamin B12 deficiency.1* Randomized, placebo-controlled trials have found that daily supplementation with Metafolin® promotes healthy levels of both folate and homocysteine.5, 6*

REFERENCES
1. EMD Millipore Corporation. (2015). Retrieved from: < http://www.emdmillipore.com/CA/en/products/small-molecule-pharmaceuticals/bulk-api/folates/metafolin/key-benefits/83Ob.
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2. Crider, KS, Yang, TP, Berry, RJ, Bailey, LB. Adv. Nutr. 2012; 3: 21–38.
3. Lamers, Y. Ann Nutr Metab. 2011; 59: 32–37.
4. Venn, BJ, Green, TJ, Moser, R, Mann, JI. Am J Clin Nutr. 2003; 77: 658–662.
5. Lamers, Y, Prinz-Langenohl, R, Moser, R, Pietrzik, K. Am J Clin Nutr. 2004; 79: 473–478.

Take one capsule daily or as recommended by your healthcare practitioner. 

Serving Size: 1 Capsule

Amount Per Serving
Folate ... 1000mcg
(from calcium L-5-methyltetrahydrofolate, Metafolin®†)

Other Ingredients: Cellulose, hypromellose

Guaranteed to contain no added wheat, starch, yeast, gluten, corn, soy, sodium, sugar, artificial coloring or flavoring, antimicrobial preservatives, dairy or animal products.

Ideal for vegans.

The capsules are made from 100% pure vegetable sources, free of preservatives and additives.

Risk Information: If you are pregnant, breastfeeding or taking any medication; or if you have any health condition, consult your healthcare practitioner prior to use. Folic acid may mask a vitamin B12 deficiency. If you are unsure whether you are taking enough vitamin B12, consult your healthcare practitioner prior to use.

Quality Assurance: Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken. Store in a cool, dry place. Keep out of reach of children.