Supports nitric oxide production and healthy blood flow*

Nitric Oxide Ultra (capsules) offers a blend of CranLoad® and citrulline to support healthy blood flow by targeting nitric oxide production and flow-mediated dilation. The formula centers around CranLoad®, a novel fruit blend developed as part of an extensive research program with the Institute of Nutrition and Functional Foods (INAF) and Université Laval in Quebec, Canada. CranLoad® delivers a unique cranberry and grape seed blend that has been the subject of several trials. Cranberries and grapes are particularly generous sources of proanthocyanidins and other polyphenols.

In addition to being antioxidants, these compounds offer specific vascular support mechanisms that are associated with enhanced endothelial function. Research indicates that CranLoad® provides statistically significant support for healthy flow-mediated dilation (FMD), an effect similar to arginine administration. FMD reflects blood vessel dilation mediated by nitric oxide synthase (NOS), an enzyme that generates the endogenous vasodilator, nitric oxide. In one study, the peak increase in brachial artery diameter following CranLoad® supplementation was 2.8% at 60 minutes.

A similar physiological effect has been demonstrated with arginine. Citrulline is included to support nitric oxide production in the blood vessel endothelium and other tissues. Research indicates that citrulline increases plasma arginine in a dose-dependent manner and to a greater degree than arginine supplementation.*

• Promotes healthy blood flow*
• Supports vascular health*
• Made with hypoallergenic, vegan ingredients

Suggested Use / Directions:
Take 2-4 capsules daily, in divided doses, between meals.

Serving Size:
2 capsules

Amount Per Serving:

L-Citrulline (free form) ... 1,000 mg
CranLoad™ proprietary blend ... 382 mg
(providing cranberry (Vaccinium macrocarpon) extract (fruit) and grape (Vitis vinifera) extract (seed))

Other Ingredients:
vegetarian capsule (cellulose, water).

Warning: If pregnant or lactating, consult your physician before taking this product. In research studies, grape seed extract has been associated with headache, abdominal pain, sore throat, nausea and cough, but these effects occur at rates similar to placebo. Consult your physician for more information.

Cranberry and grape seed may be contra-indicated with blood thinning medications. Consult your physician for more information.