Gluten free
cGMP
Soy free
Vegan
Non-GMO
Wheat free
Salt free
Sugar free
Rice free
Artificial Color / Colour Free

Mega SporeBiotic™ is a 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. This unique all-spore formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria.

MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains a healthy gut microbiome.*

Bacillus Licheniformis

Produces proteases that aid protein digestion
Produces full spectrum of B vitamins

Bacillus Indicus HU36™

Produces carotenoids: lycopene, astaxanthin, beta-carotene, and lutein
Produces quinols and vitamins

Bacillus Subtilis HU58™

Produces nattokinase and vitamin K2
Supports healthy GALT development

Bacillus Clausii

Supports immune function

Bacillus Coagulans

Produces L+ optical form of lactic acid
Supports immune function

Suggested Use / Directions:

Week 1: 1 capsule every other day

Week 2: 1 capsule daily

Week 3+: 2 capsules daily

If 1 capsule every other day causes side effects, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible side effects may include abdominal cramping, loose stools, and changes in bowel movements. Though these side effects may be uncomfortable, they are a sign that the product is working! Side effects should resolve within 2-3 days.

Serving Size:
2 Capsules

Amount Per Serving:

Proprietary Probiotic Blend ... 295 mg
Bacillus indicus (HU36™)
Bacillus licheniformis (SL-307)
Bacillus clausii (SC-109)
Bacillus subtilis (HU58™)
Bacillus coagulans (SC-208)

Other Ingredients:
Cellulose, vegetable capsule (cellulose and water).

Does not contain eggs, dairy, gluten, nuts, soy, wheat

If you are pregnant or nursing, taking any medication, or have a medical condition, consult your doctor before using this product. Keep out of reach of children. Do not use if safety seal is broken or missing.

Why is this a top pick for Bacillus (Spore-based)?

This product has been chosen as a Top Pick by Fullscript based on factors like quality, ingredients, value, and availability. Your provider’s recommendation always comes first.

This product was selected based on the factors below: MegaSporeBiotic™ is a 4 billion CFU spore-based shelf-stable probiotic blend of five clinically studied Bacillus species (including HU36™, HU58™, SC-208, SL-307, and SC-109) formulated to support gut barrier integrity, microbial diversity, and immune function. Its spores are designed to survive gastric conditions and activate in the intestine, where they help maintain a healthy gut environment.*

Learn more about our process

About enhanced testing

Every product on Fullscript meets our high quality standards – but we don’t stop there. Enhanced Testing means select products are pulled directly from Fullscript’s shelves and tested by independent labs, so what’s on the label matches what’s in the product.

Learn more about the testing methods

Top pick

Enhanced testing

Mega SporeBiotic™

Microbiome Labs

$66.99