AS4H Insulin Resistance

1.00 Softgel

afternoon

Take with food

Ongoing

Additional notes

"Most women with insulin resistance are also running low on Vitamin D — and that's not a coincidence. Vitamin D functions more like a hormone than a vitamin, and your insulin receptors actually need it to work properly. Low D = sluggish receptor response = your cells resist the signal insulin is sending. The K2 is here for a reason too. At this dose of D3, K2 acts as the traffic director — making sure calcium goes to your bones where it belongs and not into your arteries. "

1.00 Softgel

morning

Take with food

Ongoing

Additional notes

"Think of omega-3s as your body's internal anti-inflammatory crew. Insulin resistance is an inflammatory condition at its core — chronic, low-grade inflammation keeps your cells on high alert and makes them less receptive to insulin's message. EPA and DHA work to quiet that inflammatory environment so your cells can actually hear the signal again. Bonus: this specific Metagenics formula is pharmaceutical-grade, purified, and lemon-flavored — so no fishy burps. Your coworkers will thank you. "

4.00 Capsules

morning, afternoon

evening, bedtime

Take with food

Ongoing

Additional notes

"Here's the honest truth: fiber is the most underrated tool in the insulin resistance toolkit — and most of us aren't getting nearly enough. The average American woman gets about 15g per day. We need closer to 25–35g. That gap is doing real damage. Here's why fiber is non-negotiable for this stack: Glucose buffer: Soluble fiber slows the absorption of carbohydrates, flattening the blood sugar spike after meals. Flatter spike = less insulin demand = less stress on your system. Weight support: Fiber expands in your gut, increases satiety, and feeds the beneficial bacteria that regulate hunger hormones like GLP-1 and PYY — the same hormones GLP-1 medications mimic. Gut-metabolic connection: Your gut microbiome directly influences insulin sensitivity. Fiber feeds the good bugs that produce short-chain fatty acids, which improve how your cells respond to insulin. If you're on this protocol for weight loss, fiber isn't optional — it's foundational. Take 30 minutes before every meal."

2.00 Capsules

morning

Take with food

Ongoing

Additional notes

"B vitamins are your metabolic engine's spark plugs. Without them, glucose can't be properly converted into usable energy — it just sits in the bloodstream doing damage. A few standouts in this formula: B1 (Thiamine): Critical for glucose metabolism; deficiency is common in IR and diabetes B6: Supports insulin receptor sensitivity and helps reduce inflammation B12 (as methylcobalamin): The active form your body can actually use — important especially if you're taking or considering Metformin, which is known to deplete B12 Folate (as methylfolate): The bioavailable form — critical for women who carry MTHFR variants (more common than you think) and can't properly convert synthetic folic acid This isn't your grocery store B-complex. Active forms matter because your body doesn't have to do the conversion work — it gets straight to business. "

1.00 Capsule

morning

Take with food

Ongoing

Additional notes

"Magnesium is doing heavy lifting in this protocol and it is wildly under appreciated. Here's the part most people don't know: every single insulin receptor in your body requires magnesium to function. Not nice to have — requires. Studies consistently show that people with insulin resistance and type 2 diabetes have significantly lower intracellular magnesium levels. And the standard serum magnesium test your doctor orders? It misses it completely. Serum magnesium stays "normal" until you're severely depleted — because your body pulls from bones and tissues to keep serum levels stable Why Glycinate specifically: Glycinate is bound to the amino acid glycine — highly absorbable, gentle on the GI tract, no laxative effect at therapeutic doses Glycine itself has additional anti-inflammatory and blood sugar stabilizing properties This is your AM dose — take with breakfast as your metabolic workhorse"

3.00 Capsules

bedtime

Take with water

Ongoing

Additional notes

"You asked why there are two magnesiums. Here's the answer. Magnesium L-Threonate is the only form of magnesium with demonstrated ability to cross the blood-brain barrier in meaningful amounts. The brain is metabolically expensive — it runs on glucose, and when insulin resistance disrupts glucose metabolism, cognitive function, sleep architecture, and stress regulation all take a hit. This is your nighttime dose: Supports deep, restorative sleep — the phase where insulin sensitivity resets Reduces cortisol-driven glucose elevation that happens with poor sleep Supports the neurological repair and hormone regulation that only happens during deep sleep cycles Pairs beautifully with the Glycinate taken in the AM — two different mechanisms, two different windows If you're dealing with brain fog, disrupted sleep, or nighttime cortisol spikes alongside your insulin resistance — add this. It is doing something the Glycinate cannot. "

1.00 Capsule

upon waking

Take with empty stomach

Ongoing

Additional notes

"Your gut and your metabolism are in constant conversation — and insulin resistance disrupts that dialogue. Dysbiosis (an imbalanced gut microbiome) is both a contributor to and a consequence of insulin resistance. It's a loop. The Complete Commensal formula is designed to restore microbial diversity — not just dump in billions of one strain. Here's why that matters: Diverse gut bacteria produce short-chain fatty acids (SCFAs) that improve insulin sensitivity at the cellular level A healthy microbiome regulates ghrelin, GLP-1, and other hunger and satiety hormones Probiotic therapy has shown measurable improvements in fasting glucose, HbA1c, and HOMA-IR scores in clinical studies "Commensal" refers to organisms that naturally belong in the human gut — this formula is built around restoring what's supposed to be there "

2 Capsules

morning, afternoon

Ongoing

Additional notes

"Let's talk about why this berberine was selected by me personally. Standard berberine has a well-established track record — studies show it can lower fasting glucose and improve insulin sensitivity comparably to Metformin. But there's a catch: standard berberine has notoriously poor absorption. Your gut can only take in so much before the rest causes bloating, cramping, and GI distress — which is why so many women quit it. Dihydroberberine (DHB) is the reduced, more bioavailable form. Here's what that means for you: 5x more absorbable than standard berberine Lower dose needed to achieve the same or greater effect Dramatically better GI tolerance — the bloating and cramping most people experience with standard berberine? Largely eliminated. The "ES-5" designation in XYMOGEN's formulation reflects a standardized, concentrated extract — this is professional-grade, not supplement aisle berberine. This is one of the most targeted tools in this protocol for directly addressing insulin signaling at the cellular level. It works. But quality matters enormously — which is exactly why it's here and not on a drugstore shelf. Take about 15 minutes ahead of your meal to give the Berberine a head start."