††USA Functional Medicine MDs, DOs, NDs, DCs and Nutrition Professionals surveyed in 2025 for Designs for Health.

L-5-MTHF provides a natural, biologically active form of folate. Folate is essential for cell division and growth, and also works to balance the homocysteine pathway. This formula provides a generous 5 mg per capsule of folate in the bioidentical, bioactive form, 5-methyltetrahydrofolate. L-5-MTHF (the “L” signifying that it is the all-natural [6S] isomer) is the active circulating form of folate found in the body and one of the several forms found in food. In nature it is found only as this [6S] isomer, which is why DFH uses L-5-MTHF, the natural isomer, rather than the mixed (or racemic) form.

Our L-5-MTHF uses the patented folate derivative Quatrefolic®. This innovative form of folate has demonstrated high bioavailability and solubility as well as long lasting stability. Quatrefolic® L-5-MTHF helps to increase blood folate levels much better than folic acid.

Made with non-GMO ingredients.

Suggested Use / Directions:
As a dietary supplement, take one capsule per day, or as directed by your health care practitioner.

Serving Size:
1 Capsule

Amount Per Serving:
Folate ... 8500 mcg DFE
(as Quatrefolic® [6S]-5-methyltetrahydrofolate, glucosamine salt 10000 mcg)

Other Ingredients:
Organic spinach powder, microcrystalline cellulose, cellulose (capsule), L-leucine.

NOTICE
Color, size or shape may appear different between lots.

Store at room temperature. Keep out of reach of children.