Skip to main content

Up to 10% off

when you sign up


  • Gluten free

  • Dairy free

  • Animal product free

  • Vegan

  • Wheat free

  • Milk free

  • Artificial preservative free

  • Yeast free

  • Artificial Flavor / Flavour Free

Cortisol Manager – The Stress Hormone Stabilizer

Cortisol, often referred to as the “stress hormone,” is produced by the adrenal cortex in response to signals from the hypothalamus and pituitary gland, as part of the hypothalamic-pituitary-adrenal (HPA) axis. Cortisol is perhaps the most important hormone involved in the adaptation process.

Upon exposure to acute stressors, cortisol secretion can generally help maintain homeostasis in the body. Because of its central role as a “first responder” and its capability to modulate multiple critical physiological functions, cortisol is often seen as the bridge between stress and its health consequences.

Variations of cortisol secretion can be an indicator of how well a body is coping with stress. Cortisol production is generally at its peak in the early hours of the morning and then gradually declines over the course of the day.

Cortisol Manager has been formulated with stress-reducing ingredients and botanicals to promote relaxation, help alleviate fatigue, and support healthy cortisol levels.* By balancing cortisol levels, Cortisol Manager can help reduce stress, which supports a restful night's sleep without diminishing daytime alertness.* Cortisol Manager is formulated with:

• Ashwagandha (Sensoril brand)
• L-theanine
• Phosphatidylserine
• Magnolia
• Epimedium

Suggested Use / Directions:
Adults take 1 tablet before bedtime or as recommended by a healthcare professional. Increase to 2 tablets during times of high stress. For nightly use.

Serving Size:
2 Tablets

Amount Per Serving:
Calories … 10
Total Carbohydrate … 1g
Sodium … 10mg
Stress-Reducing Proprietary Blend … 500mg
Ashwagandha (Withania somnifera) (Sensoril® brand) (root, leaf) Extract, L-theanine
Cortisol-Reducing Proprietary Blend … 450mg
Magnolia (Magnolia officinalis) (bark) Extract standardized to 2% honokiol and 1% magnolol, Epimedium (Epimedium spp.) (aerial parts) Extract
Phosphatidylserine … 100mg
(from soybean lecithin)

Other Ingredients:
cellulose, sodium croscarmellose, stearic acid, calcium silicate, magnesium stearate, silica, hypromellose, glycerin


Warning: Do not use if you are pregnant or nursing. If you are taking any medications, consult a healthcare professional before use. Individuals with diabetes should monitor blood glucose levels closely while taking this product. Keep out of reach of children. Safety sealed with inner seal. Do not use if seal is broken or missing. Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Why is this a top pick for Stress support?

This product has been chosen as a Top Pick by Fullscript based on factors like quality, ingredients, value, and availability. Your provider’s recommendation always comes first.

This product was selected based on the factors below: Provides a proprietary blend per serving featuring Sensoril® ashwagandha and L-theanine, combined with magnolia, epimedium, and phosphatidylserine from soy lecithin.* Sensoril® is a branded ashwagandha extract studied for its role in supporting balanced cortisol levels and a healthy stress response.* This multi-ingredient formula is designed to support relaxation and promote restful sleep through complementary mechanisms.* The inclusion of targeted herbal extracts and phosphatidylserine highlights a combination approach to supporting adaptive stress response pathways.*

Learn more about our process

About enhanced testing

Every product on Fullscript meets our high quality standards – but we don’t stop there. Enhanced Testing means select products are pulled directly from Fullscript’s shelves and tested by independent labs, so what’s on the label matches what’s in the product.

Learn more about the testing methods

Top pick

Enhanced testing

Cortisol Manager

Integrative Therapeutics

$26.99

Sign up for exclusive store pricing