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  • Gluten free

  • Vegan

  • Non-GMO

  • Vegetarian

  • Organic

  • Mushroom Supplement for Immune Support: This herbal mushroom supplement aids a healthy and balanced immune response with comprehensive support*
  • 17-Species Mushroom Supplement: Our herbal supplement is made with Lion's Mane, Reishi, Chaga, Cordyceps, Maitake, Royal Sun Blazei, Mesima and more for unique mushroom support*
  • About Host Defense: Host Defense Mushrooms was founded by renowned mycologist Paul Stamets; our mushroom mycelium is certified organic, non-GMO, gluten-free, and grown in the USA*
  • Powered by Mushroom Mycelium: Our organic mushroom mycelium is grown on organic brown rice substrate; third-party studies show that mushroom mycelium and fermented rice substrate support your health*


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested Use / Directions:
As a dietary supplement, take 2 capsules once per day. Can be taken with food or without on an empty stomach or as recommended by your healthcare advisor.

Serving Size:
2 capsules

Amount Per Serving:

Calories ... 5
Total Carbohydrate ... <1g
Chaga (Inonotus obliquus) mycelium‡/rice biomass‡ ... 148 mg†
Maitake (Grifola frondosa) mycelium‡/rice biomass‡ ... 142 mg†
Reishi (Ganoderma lucidum s.l.) mycelium‡/rice biomass‡ ... 110 mg†
Cordyceps (Cordyceps militaris) mycelium‡/rice biomass‡ ... 100 mg†
Royal Sun Blazei (Agaricus brasiliensis f. blazei) mycelium‡/rice biomass‡ ... 80 mg†
Enokitake (Flammulina velutipes) mycelium‡/rice biomass‡ ... 80 mg†
Mesima (Phellinus linteus) mycelium‡/rice biomass‡ ... 76 mg†
Lion’s Mane (Hericium erinaceus) mycelium‡/rice biomass‡ ... 64 mg†
Turkey Tails (Trametes versicolor) mycelium‡/rice biomass‡ ... 48 mg†
Oyster Mushroom (Pleurotus ostreatus) mycelium‡/rice biomass‡ ... 48 mg†
Artist’s Conk (Ganoderma applanatum) mycelium‡/rice biomass‡ ... 30 mg†
Oregon Ganoderma (Ganoderma oregonense) mycelium‡/rice biomass‡ ... 30 mg†
Agarikon (Fomitopsis officinalis) mycelium‡/rice biomass‡ ... 30 mg†
Amadou (Fomes fomentarius) mycelium‡/rice biomass‡ ... 20 mg†
Shiitake (Lentinula edodes) mycelium‡/rice biomass‡ ... 20 mg†
Birch Polypore (Piptoporus betulinus) mycelium‡/rice biomass‡ ... 12 mg†
Split Gill Polypore (Schizophyllum commune) mycelium‡/rice biomass‡ ... 12 mg†


Other Ingredients:
dried myceliated brown rice, pullulan (capsule).

Other Ingredients: dried myceliated brown rice, pullulan (capsule).


Warning: If you have a medical condition, are taking medications, or are pregnant or nursing, consult your healthcare professional before using this product. Keep out of reach of children.
Why is this a top pick for Mushrooms?

This product has been chosen as a Top Pick by Fullscript based on factors like quality, ingredients, value, and availability. Your provider’s recommendation always comes first.

This product was selected based on the factors below: Activated, optimally dried organic Reishi mycelium provides a full spectrum of polysaccharides, ganoderic acids and extracellular prebiotic fibers. In vitro studies demonstrate immune support effects; clinical trials of generic, standardized Reishi extracts show support for NK-cell activity and stress. No published studies have evaluated Host Defense’s proprietary activated-mycelium formula. USDA-organic, non-GMO, third-party tested for contaminants.*

Learn more about our process

About enhanced testing

Every product on Fullscript meets our high quality standards – but we don’t stop there. Enhanced Testing means select products are pulled directly from Fullscript’s shelves and tested by independent labs, so what’s on the label matches what’s in the product.

Learn more about the testing methods

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Host Defense

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