††USA Functional Medicine MDs, DOs, NDs, DCs and Nutrition Professionals surveyed in 2025 for Designs for Health.

Tri-Butyrin Supreme™ represents a new approach to gut health and immune function by modulating intestinal flora, promoting colonocyte health and supporting proper gut permeability. This product features CoreBiome™, a patent pending form of tributyrin, consisting of three molecules of butyric acid (butyrate) bound to glycerol. Each softgel provides 300 mg of this novel, broad-application compound.
Suggested Use:
Take one softgel per day or as directed by your health care practitioner.


Serving Size: 1 Softgel

Amount Per Serving
Tributyrin … 300 mg
(as Corebiome™)

Other Ingredients: Bovine gelatin, purified water, glycerine, black cumin seed oil (Nigella sativa), medium chain triglycerides.
Keep out of reach of children.