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Histamine Support

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There are a multitude of factors that contribute to histamine intolerance. Moreover, there are many ways to treat histamine intolerance, based on the root cause(s). For example, you may have gut irritation which is slowing down your diamine oxidase (DAO) enzyme, preventing it from breaking down histamine from food properly. You may also have a genetic single nucleotide polymorphism (SNP) in your DAO gene, that contributes to naturally slower DAO activity. What does this mean? It means the amount of histamine in your gut may be higher than normal due to a lack of DAO enzyme activity. However, DAO supplementation may not support  all  of your concerns. You may also need to do an elimination diet, such as a low-histamine diet, and address gut issues with a qualified healthcare practitioner. All of these pieces are crucial components to learning how to treat and manage histamine intolerance. Figuring out the primary cause(s) will help you to choose the perfect formula to support healthy histamine metabolism and a normal response to histamine from food. 6 Supplements to Support Healthy Histamine Levels 1. Histamine-Friendly Probiotic -  ProBiota HistaminX Histamine intolerance is exacerbated by poor gut health. (4) Your gut bacteria play essential roles in supporting healthy inflammatory processes, digestion, and even histamine metabolism. You have probably heard that probiotics are a powerful tool for adding good bacteria back into your intestines. But many probiotics can produce  histamine. Therefore, it is important to find a probiotic that is formulated to avoid strains known to produce histamine in the gut. ProBiota HistaminX which is a one-of-a-kind probiotic formulated to avoid strains known to produce excess histamine in the gut. These probiotic species include both lactobacillus and  bifidobacterium , specifically chosen to support a healthy microbiome for people intolerant to histamine. It supports your gut’s natural response to ingested histamine, healthy bacterial balance, healthy skin, and normal inflammatory processes. 2. DAO Enzyme + Cofactors - Histamine Block Plus DAO is the primary enzyme responsible for breaking down histamine in your digestive tract. However, there are other enzymes involved in your histamine pathway as well. These enzymes require certain nutrient cofactors to function optimally. For example, if you are deficient in copper and vitamin B6, DAO may not be able to efficiently break down histamine. Dr. Ben Lynch formulated Histamine Block Plus, a full histamine pathway support formula containing the necessary cofactor nutrients for system-wide histamine metabolism and optimal DAO functionality. Histamine is broken down via DAO and another enzyme known as histamine methyltransferase (HNMT). While both enzymes may be involved in overall histamine response, they can malfunction in the presence of toxic byproducts from histamine breakdown. These toxic byproducts are known as imidazole acetaldehyde and N-methylhistamine. They can accumulate in the body and slow down both DAO and HNMT enzymes, potentially contributing to histamine intolerance. Histamine Block Plus contains nutrients to help metabolize these toxic byproducts, to keep the  entire  histamine pathway working smoothly. By supporting each of these enzymes with their nutrient cofactors, you can improve the overall functionality of histamine breakdown. Those nutrients are known as “cofactors.” They are what your body requires to process histamine down the pathways you see in this diagram. They are literally the key that turns ‘on’ your enzymes responsible for supporting histamine levels throughout your entire body. The metabolism of histamine is also known to create toxic byproducts, such as ammonia, hydrogen peroxide, and acetaldehyde. These byproducts can cause side effects and damage to cells. Histamine Block Plus also contains the cofactors needed to break down the toxic byproducts of histamine. Histamine Block Plus provides 2.1 mg per serving, a lower strength of DAO compared to the original Histamine Block. However, it contains 12 additional nutrients that support the healthy processing and metabolism of histamine by targeting several enzymes in the histamine pathway (see pathway diagram above). 3. Herbal Support - HistaminX Histamine can contribute to nose, lung, and eye irritation if it is not appropriately supported throughout the body. It also plays a major role in a healthy immune system. Supporting healthy histamine means also supporting a healthy immune response. When too much histamine is released from your immune cells, it can cause the immune system to overreact. This can trigger the release of even more histamine, in a vicious cycle. This is where HistaminX comes in. Dr. Lynch launched this supportive blend of flavonoids and other plant compounds which are known for supporting healthy respiratory responses, normal mucus membranes, and healthy histamine release. Bioflavonoids and certain plant compounds have natural immune regulating properties and are found in high amounts in citrus fruits. This formula blend contains compounds such as luteolin, rutin, quercetin, stinging nettle extract, bromelain (from pineapple), and glucoraphanin (from broccoli).  Each of these plays a unique role in supporting a healthy immune system response, histamine processing, respiratory health, and degradation of potentially toxic histamine metabolism byproducts (i.e. hydrogen peroxide and ammonia). This product is perfect for traveling and through any season, when you need to support a healthy histamine response. 4. Vitamin C - Optimal Liposomal Vitamin C Plus Vitamin C plays a major role in histamine release and DAO production. Vitamin C is extremely important in the production of DAO and mast cell modulation. In addition, it is critical for a healthy immune system. 5. Magnesium glycinate 200–400 mg Evening, 1 hr before bed Calms mast cell activity; supports sleep Magnesium Glycinate Powder by Seeking Health provides a bioavailable bisglycinate chelate form of magnesium in a flexible powder format. This convenient powder makes adjusting dosage for individual needs easy, as it can be added to water, juice or your favorite food or beverage Suggested Use / Directions: Blend, shake, or briskly mix 1 scoop, 1-2 times daily 6.Methyl B12 with L-Methylfolate by Seeking Health provide 800 mcg of pure non-racemic L-methylfolate in an easy-to deliver lozenge, along with two active “coenzyme” forms of vitamin B12. As “coenzyme” forms, methylcobalamin and adenosylcobalamin are the forms required by certain B12-dependent enzymes and reactions within the body. Similarly, L-5-methyltetrahydrofolate is considered an “active” form of folate - the body’s most prevalent form of folate in plasma.*

Anti-Histamine Support

Bone Support

Building Bone from the Inside Out Osteoporosis isn't just a calcium problem — and a calcium pill alone isn't the solution. Bone is living tissue. It's constantly being broken down and rebuilt, and that process depends on a coordinated team of nutrients working together. When key players are missing, your body can't build the strong, resilient bone matrix you need — no matter how much calcium you take. That's the root cause most conventional approaches miss. Our supplement protocol is designed to support the entire bone-building system: the minerals that form the structural matrix, the nutrients that direct calcium into bone rather than soft tissue, and the co-factors that drive the cellular machinery of bone remodeling. This isn't about patching a warning light. It's about giving your body what it actually needs to fix the engine.

Natural Anit-Inflammation Protocol

Natural Anit-Inflammation Protocol resource 1

Using KappArest® and Intenzyme Forte® with SPM Active® for Inflammatory Pain A simple guide for patients Why this combination is used Inflammatory joint pain typically involves three issues: Excess inflammatory signaling (driving pain and swelling) Build-up of inflammatory byproducts in the tissues Poor resolution of inflammation (the body doesn’t “turn off” inflammation efficiently) This protocol addresses all three: KappArest → helps reduce inflammatory signaling Intenzyme Forte → helps clear inflammatory debris SPM Active → helps actively resolve inflammation Why SPMs instead of standard omega-3s? Most people are familiar with fish oil (omega-3s), but there’s an important distinction: Omega-3s (EPA/DHA) Provide raw materials your body uses to manage inflammation Require conversion into active compounds Conversion can be inefficient, especially with: chronic inflammation aging metabolic issues SPMs (Specialized Pro-Resolving Mediators) Are the active end-products made from omega-3s Directly signal the body to: turn off inflammation clear inflammatory cells support tissue healing Simple analogy: Omega-3s = ingredients SPMs = finished product your body actually uses 👉 This is why SPMs are often more effective, especially in chronic or stubborn inflammation where the body is not resolving inflammation properly. How each part works KappArest® Plant-based anti-inflammatory support (turmeric, boswellia, resveratrol, etc.) Helps reduce inflammatory chemicals in the body Best for: Chronic joint pain Autoimmune-related inflammation Activity-related flare-ups Intenzyme Forte® Systemic enzymes that break down inflammatory proteins Supports circulation and tissue recovery Important: Take away from food for joint benefits Best for: Swelling and stiffness Injury or flare-related inflammation SPM Active® Contains specialized pro-resolving mediators derived from fish oil Helps the body actively shut down inflammation and promote healing Best for: Chronic inflammation that doesn’t fully resolve Ongoing stiffness or slow recovery Patients not responding well to standard omega-3s Dosing Guidelines For Chronic (Ongoing) Joint Pain KappArest® 2 capsules, 2–3 times daily With or without food Intenzyme Forte® 2 capsules, 2–3 times daily Empty stomach only 30–60 minutes before meals Or 2 hours after meals SPM Active® 2 softgels, 1–2 times daily Take with meals For Acute Flare-Ups (Increased Pain or Swelling) KappArest® 2 capsules, 3–4 times daily Intenzyme Forte® 3–5 capsules, 2–4 times daily Always on an empty stomach SPM Active® 2 softgels, 2–3 times daily Take with meals What to Expect Intenzyme Forte® may help reduce swelling within a few days KappArest® helps calm inflammation over 1–2 weeks SPM Active® supports resolution and recovery over 2–4 weeks Best results come with consistent use Contraindications (When to Avoid or Use Caution) Do not use or consult your healthcare provider if you: Are taking blood thinners (such as Warfarin) Have a bleeding disorder Are scheduled for surgery (stop at least 1–2 weeks prior unless directed otherwise) Are pregnant or breastfeeding Have known allergies to: Fish or seafood Pineapple or papaya (enzyme sources) Use caution if you: Take anti-inflammatory medications (NSAIDs or steroids) Have gallbladder disease Have a history of ulcers or sensitive digestion Potential Side Effects Most people tolerate this protocol well, but possible side effects include: KappArest® Mild digestive upset Heartburn Intenzyme Forte® Nausea if taken incorrectly or at high doses Rarely: increased bruising or bleeding risk SPM Active® Mild digestive upset Occasional fishy aftertaste Loose stools at higher doses Important Considerations Do not take Intenzyme Forte® with food if using it for joint pain Higher doses are intended for short-term use during flare-ups This protocol helps manage inflammation but does not replace addressing root causes such as: Diet quality Blood sugar balance Sleep Gut health FDA & Medical Disclaimer These statements have not been evaluated by the Food and Drug Administration (FDA) These products are not intended to diagnose, treat, cure, or prevent any disease This information is for educational purposes only and is not a substitute for medical advice Always consult your healthcare provider before starting or changing any supplement regimen, especially if you have a medical condition or take prescription medications Key Takeaway KappArest® → helps reduce inflammatory signaling Intenzyme Forte® → helps clear inflammatory buildup SPM Active® → helps actively resolve inflammation Together, they provide a more complete approach to reducing joint pain and supporting recovery.

Plantar Fasciitis

These are the supplements recommended for Plantar Fasciitis Vitamin C: 1000 mg three times daily – collagen synthesis & repair. KapArrest (Biotics Research): Herbal anti-inflammatory blend. Fish oil (EPA/DHA): 2–3 g daily – systemic anti-inflammatory. Collagen powder: 10–20 g daily with vitamin C – tendon and fascia support. DMSO topical (diluted): Improves circulation, reduces pain, enhances healing. buy at https://www.pharmadmso.com/

Maca for Perimenopause and Postmenopause

Maca (Lepidium meyenii) is a root vegetable native to the Peruvian Andes and has been traditionally used as an adaptogen to enhance energy, libido, and overall hormonal balance. In recent years, it has gained popularity as a natural remedy for managing symptoms associated with perimenopause and postmenopause . How Maca Supports Women in Perimenopause and Postmenopause Maca does not contain estrogen or phytoestrogens but is believed to work through the hypothalamic-pituitary-adrenal (HPA) axis to support hormonal balance. This means it may help regulate hormone production rather than supplying external hormones. FemmenessencePRO PERI: contains MacaLife a concentrated, highly bioavailable, proprietary formulation of Lepidium peruvianum (maca) phenotypes specifically formulated for women to support the hypothalamic - pituitary - thyroid - adrenal - ovarian (HPTAO) axis and perimenopausal symptoms. FemmenessencePRO PERI is the first natural product to demonstrate, in published clinical trials, statistically significant effects on hormones in perimenopausal women by supporting the body’s own production. Clinical results in perimenopausal women showed a 72-84% success rate in reducing menopausal symptom relief within the first box and improvements in endogenous hormones, including estradiol and progesterone. After four months in clinical trials, postmenopausal women taking FemmenessencePRO PERI also had improved lipid profiles and BMI.  Supports: -Hormone balance* -Hot flashes and night sweats* -Vaginal dryness* -Libido and sexual health* -Mood and improved outlook on life* -Energy levels* -Healthy body weight* -Healthy cholesterol and triglyceride levels within normal ranges* Important information about maca: There are 17 different phenotypes of maca that can be different colors, have different DNA, different analytical profiles, and most importantly, different physiological effects. MacaLife® contains 25% Maca-GO and 75% another phenotype specifically for perimenopausal women to support hormone balance and reduce menopausal symptoms. PUBLISHED ARTICLES: Maca-GO: The Science, Publications, and Clinical Applications for Hormone Health Download Paper Therapeutic effect of Lepidium peruvianum Chacon (Maca-GO) used as a non-hormonal alternative to HRT in peri-menopausal women. International Journal of Biomedical Science 2006: Vol. 2, No. 2. 143.  PubMed - Full Article Short and Long-Term Physiological Responses of Male and Female Rats to Two Dietary Levels of Pre-Gelatinized Maca (Maca-GO) (Lepidium peruvianum Chacon). International Journal of Biomedical Science. 1 (2): 13-28. PubMed - Full Article Pre-Gelatinised Maca (Maca-GO) (Lepidium peruvianum Chacon) As Non-Hormonal Herbal Remedy to Reduce Menopausal Symptoms In Pre- And Post-Menopausal Women. Basic Clinical Pharmacology and Toxicology. Vol. 97, Supp l (1): 48. Download Abstract   Suggested Use: Take 1 capsule twice daily with 8-16oz. of water before or between meals. The first serving is to be taking in the morning, and the second in the afternoon - ideally 30 minutes before a low in energy. Not to be taken in conjunction with hormone suppressing medications such as tamoxifen. Not to be taken if nursing or past the second trimester if pregnant, unless directed by your healthcare professional. Consult your healthcare professional before starting Femmenessence if you are taking medication.