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5-Hydroxytryptophan

Thorne

$33.00

(MSRP)

5-Hydroxytryptophan product image
SKU: THO-SA503

The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings.* There are several ways to support a healthy serotonin level. L-tryptophan and 5-Hydroxytryptophan (5-HTP) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system.* And 5-HTP can be taken with meals without reducing its effectiveness.*

 

5-Hydroxytryptophan (5-HTP) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase – which is the rate-limiting step in the synthesis of serotonin – and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.* 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream.* Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily.*

 

To further facilitate serotonin production, Thorne's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.

 

Each lot is thoroughly tested for contaminants, including Peak X, and is Peak X free.


Take 1-2 capsules three times daily or as recommended by your health professional.


Serving Size: 2 Capsules

Amount Per Serving
5-Hydroxytryptophan
... 100mg
Vitamin B6 ... 6.8mg
(Pyridoxal 5'-Phosphate)

Other Ingredients: Hypromellose Capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide
 

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

 

PREGNANCY WARNING

If pregnant or nursing, do not use this product.

 

INTERACTIONS/CONTRAINDICATIONS

5-Hydroxytryptophan should be used with caution in an individual currently being treated with an SSRI, MAO inhibitor, or other antidepressant medication.


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