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Celiac Disease Diagnostic Panel - Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.
5 biomarkers
Celiac disease (CD) is often undiagnosed and is caused in genetically predisposed individuals by abnormal intestinal permeability and abnormal immune response to gluten, a protein complex found in wheat, barley, spelt and rye. The inflammatory autoimmune response damages the lining of the small bowel and is associated with diarrhea, bloating, fatigue, nutritional deficiencies, and systemic autoimmune conditions. Gluten sensitivity can cause similar symptoms but without the same level of tissue damage. The Celiac & Gluten Sensitivity profile from Doctor’s Data helps differentiate between CD and gluten sensitivity by evaluating the serum titers of IgA for deamidated gliadin peptide and gliadin.
6 biomarkers
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