
Comprehensive Hormone Plus Profile
Doctor's Data
Sample type: Saliva
Requires fasting: No
At home test
Details
Research indicates this profile could be considered for those at an increased risk of developing breast cancer or those with a family history of breast cancer. The Comprehensive Plus Hormone Profile reports hormone levels and calculates two important ratios. The Estrogen Quotient is a simple ratio of cancer-protective estrogen (E3) in relation to proliferative estrogens (E1 and E2) – used to assess breast cancer risk. And the Pg/E2 ratio which assesses the relationship between the cellular proliferating, estradiol, and growth-mitigating, progesterone, in your body.
- Cortisol Evening
- Cortisol Night
- Cortisol Noon
- Cortisol Morning - AM30
- Estriol
- Testosterone
- Estrogen quotient
- Estradiol, Saliva
- Estrone, Saliva
- Progesterone, Saliva
Estimated days for results: Results should arrive 3 to 5 days after the lab receives samples.
Hormones are powerful molecules essential for maintaining physical and mental health. We frequently think of estrogen as being a female hormone, and testosterone as being a male hormone. But men AND women make both, plus several more that need to be in balance for optimum health. An imbalance of any one hormone can throw your physical and mental health out of balance, causing aggravating and even serious health problems.
One size does not fit all when it comes to hormones. For decades western medicine has prescribed hormone replacement therapy as if everyone needed the same thing and the same amount. Nothing could be further from the truth. Your hormones are like your fingerprints and in order to achieve optimal health, you need to know what your specific imbalances are. Female and male hormone tests can help identify these imbalances.
There are several ways to test for hormones (saliva, serum and urine). Saliva is the best method to test the active/bioavailable portion of hormones, which are reflective of tissue levels. If your patient is seeking bio-identical hormone replacement (BHRT), you'll need to know active hormone levels. In addition, if using a topical (transdermal) hormone preparation for treatment, saliva testing is the most accurate tool to measure and monitor hormone status.
Useful for:
- Increased risk of developing breast cancer
- History of breast cancer or other hormonally sensitive cancers
- Personal or family history of autoimmune disease
- PCOS
3–5 business days
- Add-on: Secretory IgA
- Follow the test collection instructions here.
- If you are a menstruating woman, collect one day during days 19-23 of your menstrual cycle (assuming a 28-day cycle). Day 1 of your cycle is the first day of your period.
- If you are a man or a non-menstruating woman, collect on any day.
Hormone Use Instructions
- DO NOT discontinue any prescription medications without first consulting your healthcare provider.
- Topical hormones:
- Your last dose before sample collection should be 12-24 hours before collecting your first sample.
- DO NOT use on the day of saliva collection.
- Sublingual hormones or troches:
- Your last dose before sample collection should be 24-36 hours before collecting your first sample.
- Drink 2 full glasses of water (about 16 oz) after taking your last dose to clean the tissues.
- DO NOT take on the day of saliva collection.
- Hormone injections, subcutaneous pellets, or transdermal patches:
- Collect your samples at the halfway point between doses.
- Oral hormones (pills):
- Use as prescribed on the day of collection.
Cortisol or Cortisol-Containing Products
- If you are taking a cortisol supplement, glucocorticoid, or cortisol-containing medication, consult with your healthcare provider before collecting your samples.
- It is recommended to stop using these products 5 days before sample collection.
Day of Collection
- Avoid supplements and non-essential medications. DO NOT discontinue any prescription medications without first consulting your healthcare provider.
- Avoid caffeine-containing foods and beverages.
- Avoid anti-aging creams.
- Avoid the following for 1 hour before collecting each sample:
- Eating
- Drinking
- Avoid the following for 30 minutes before collecting each sample:
- Brushing your teeth
- Flossing your teeth
- Having dental work done
- 10 minutes before each saliva collection, rinse your mouth with water.
Collection Schedule
- Sample 1: 30 minutes after awakening
- Sample 2: Before lunch
- Sample 3: Before dinner
- Sample 4: Before bed
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island




