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Diagnostic Solutions Laboratory

Calprotectin (Stand-Alone)

Diagnostic Solutions Laboratory

Sample type: Stool

Requires fasting: No

At home test


Details

Calprotectin is a 36 kDa heterodimeric calcium bind protein that comprises approximately 60% of the cytosolic proteins present in inflammatory cells. Therefore, during intestinal inflammation, calprotectin quantification can be used to measure the level of neutrophils present in the intestinal lumen.


  • Calprotectin, Stool

Estimated days for results: Results should arrive 7 - 14 business days after the lab receives samples.

Fecal calprotectin has been shown to increase at a faster rate than serum calprotectin suggesting that fecal calprotectin quantification is a significant biomarker for early stage intestinal mucosal inflammation. In addition, calprotectin is highly resistant to degradation by gastric proteases making it an ideal fecal biomarker for non-invasive detection of intestinal inflammation.

A wide variety of conditions can result in increased neutrophils present in the GI tract including: 

  • Inflammatory Bowel Disease (IBD)
  • Crohn’s Disease (CD)
  • Food/protein sensitivities
  • Ulcerative Colitis (UC)
  • Infectious (pro-inflammatory) organisms

7–14 business days


  • Gastrointestinal
  • Tumor markers

  • Add-on - Fecal Gluten Peptide (Stool Gluten)
  • Add-on - Zonulin (Gut Permeability)

Continue taking all medications unless otherwise directed by your provider.

This test can be taken at any time.

No special preparation or timing is required.

DO NOT discard the pink liquid in the specimen vial.

DO NOT freeze your sample.

Save the printed requisition form you received in your Fullscript box and send it back with your sample.

Your sample must be CLEARLY labeled and arrive at the lab with a completed test requisition form for the lab to analyze it.

Your sample can only be shipped Monday - Friday.

Your sample must be received by the lab within 5 days of collection. It is ONLY VIABLE FOR 10 DAYS post-collection.

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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