
Histamine Clearance Index
Diagnostic Solutions Laboratory
Sample type: Whole blood
Requires fasting: No
Phlebotomy is required for this test
Details
The Histamine Clearance Index™ helps evaluate impaired histamine elimination, which may occur as a result of reduced DAO activity. By assessing the functional capacity of DAO, the Histamine Clearance Index™ offers deeper clinical insight than standalone measurements of histamine or DAO levels.
- Histamine Clearance Index
Estimated days for results: Results should arrive 7 business days after the lab receives samples.
The Histamine Clearance Index™ is a targeted histamine intolerance test that evaluates the body’s ability to break down and eliminate histamine. This test helps practitioners assess impaired histamine clearance associated with reduced or inhibited diamine oxidase (DAO) activity, supporting clinical evaluation in patients with multi-system or allergy-like symptoms.
7 business days
Before You Start
- Please read the provided test collection instructions.
- Continue taking any nutritional supplements and medications unless your healthcare provider says otherwise.
Day Before Sample Collection
- Hydrate the day before sample collection.
Day of Collection
- DO NOT refrigerate or freeze your sample.
- Save the printed requisition form you received in your Fullscript box and send it back with your sample.
- Your sample must be clearly labeled and arrive at the lab with a completed test requisition form for the lab to be analyzed.
- Ship your sample on the same day it is collected, Monday–Thursday only.
Minimum age:
2
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island




