Zonulin Profile (Stool)
Diagnostic Solutions Laboratory
Sample type: Stool
Requires fasting: No
At home test
Details
This test measures zonulin, a protein that modulates the permeability of tight junctions between cells of the wall of the digestive tract. It is used to help diagnose intestinal permeability/leaky gut and can be ordered as an add-on to the GI-MAP.
- Zonulin
Estimated days for results: Results should arrive 7 - 14 business days after the lab receives samples.
Diagnostic Solutions Laboratory's Zonulin Profile is a diagnostic test that measures the level of zonulin in the body. Zonulin is a protein that regulates the permeability of the tight junctions between cells in the digestive tract. It controls the flow of molecules, including nutrients and antigens, between the bloodstream and the intestinal lumen.
Zonulin has emerged as a popular serological marker to assess the integrity of the intestinal mucosal barrier. Elevated levels of zonulin have been associated with autoimmune diseases, such as celiac disease.
7–14 business days
- Add-on - Fecal Gluten Peptide (Stool Gluten)
Step by Step Stool Collection Instructions
NOTE: Please review all instructions and collection kit components before starting your sample collection. DO NOT discontinue taking prescription medications unless directed by your physician.
Step 1 – Write the Patient Name, Date of Birth, and Collection Date on the Specimen Vial.
Step 2 – If possible, void urine prior to collecting stool to avoid mixing it with your stool sample. Put gloves on and pass stool into provided Collection Tray.
Step 3 – Using the spoon attached to the cap of the specimen vial, spoon stool from multiple areas of the sample (ie., from at least 4 areas going left to right) into the vial.
Fill vial to ABOVE THE FILL LINE indicated on the label. Don't overfill. The cap should close without spillover. Failure to add sufficient sample may result in the laboratory not being able to process the sample. DO NOT DISCARD THE PINK LIQUID IN THE SPECIMEN VIAL.
Step 4 – Carefully mix stool and fluid with the spoon (attached to the cap). Replace cap tightly and shake vial vigorously for 30 seconds.
Step 5 – A) Fill out the Test Request Form completely and place form into the document holder of the Specimen Bag.
NOTE: Be sure to write the date of sample collection on the form. Payment type must be completed and payment included to process sample.
B) Place capped Specimen Vial containing the collected stool sample into the Specimen Bag along with Absorbent Pad and seal the bag.
C) Place the Specimen Bag with the collected sample and Test Request Form into the Kit Box.
D) Ship completed Kit Box back to Diagnostic Solutions Laboratory using the FedEx Clinical Pak Mailer provided. Please make note of tracking numbers when shipping your package. See shipping instructions below.**
Stool sample must be received within 6 days of collection. If you cannot ship the specimen on the day of collection, please refrigerate and ship as soon as possible, preferably within 3 days.
NOTE: Please review all instructions and collection kit components before starting your sample collection. DO NOT discontinue taking prescription medications unless directed by your physician.
Step 1 – Write the Patient Name, Date of Birth, and Collection Date on the Specimen Vial.
Step 2 – If possible, void urine prior to collecting stool to avoid mixing it with your stool sample. Put gloves on and pass stool into provided Collection Tray.
Step 3 – Using the spoon attached to the cap of the specimen vial, spoon stool from multiple areas of the sample (ie., from at least 4 areas going left to right) into the vial.
Fill vial to ABOVE THE FILL LINE indicated on the label. Don't overfill. The cap should close without spillover. Failure to add sufficient sample may result in the laboratory not being able to process the sample. DO NOT DISCARD THE PINK LIQUID IN THE SPECIMEN VIAL.
Step 4 – Carefully mix stool and fluid with the spoon (attached to the cap). Replace cap tightly and shake vial vigorously for 30 seconds.
Step 5 – A) Fill out the Test Request Form completely and place form into the document holder of the Specimen Bag.
NOTE: Be sure to write the date of sample collection on the form. Payment type must be completed and payment included to process sample.
B) Place capped Specimen Vial containing the collected stool sample into the Specimen Bag along with Absorbent Pad and seal the bag.
C) Place the Specimen Bag with the collected sample and Test Request Form into the Kit Box.
D) Ship completed Kit Box back to Diagnostic Solutions Laboratory using the FedEx Clinical Pak Mailer provided. Please make note of tracking numbers when shipping your package. See shipping instructions below.**
Stool sample must be received within 6 days of collection. If you cannot ship the specimen on the day of collection, please refrigerate and ship as soon as possible, preferably within 3 days.
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
