DUTCH Plus
Precision Analytical (DUTCH)
Sample type: Saliva, Urine
Requires fasting: No
At home test
Details
The DUTCH Plus® combines the flagship dried urine test with a saliva test to maximize the available information on sex and adrenal hormone production and metabolism. This extensive profile provides insights into the overall diurnal pattern of free cortisol and cortisone, the total distribution of cortisol metabolites, and the cortisol awakening response (CAR). Organic acid tests provide further insight into potential nutritional deficiencies, oxidative stress, gut dysbiosis, and more. The DUTCH Plus® is an essential tool for optimizing treatment plans and addressing hormone-related symptoms and conditions.
- 3-Hydroxyisovaleric Acid
- 4-Hydroxyestrone
- 2-Hydroxyestrone
- Cortisone Night
- Cortisone Evening
- Cortisol Evening
- Cortisol Night
- Cortisol Morning - AM60
- Cortisol Morning - AM30
- Cortisol Waking
- b-Pregnanediol
- Cortisone Morning - AM60
- Cortisone Morning - AM30
- Cortisone Waking
- Indican
- b-Tetrahydrocortisol
- Total Estrogen
- Quinolinic Acid
- Melatonin
- Estriol
- Metabolized Cortisol
- Etiocholanolone
- 8-Hydroxy-2-deoxyguanosine
- 16-Hydroxyestrone
- Vanillylmandelic Acid
- Pyroglutamic Acid
- Kynurenic Acid
- Homovanillic Acid
- 5a-Dihydrotestosterone
- Xanthurenic Acid
- b-Tetrahydrocortisone
- a-Tetrahydrocortisol
- Epi-Testosterone
- 5b-Androstanediol
- 5a-Androstanediol
- Androsterone
- a-Pregnanediol
- Testosterone
- Estradiol, Urine
- Estrone, Urine
- Progesterone, Urine
- Dehydroepiandrosterone Sulfate
- 2-methoxyestrone (2-m-e1)
- 2-hydroxyestradiol (2-oh-e2)
- 4-hydroxyestradiol (4-oh-e2)
- Creatinine (Urine)
- Methylmalonic Acid (MMA), Urine
Estimated days for results: Results should arrive within 10 business days after the lab receives samples.
This test offers further insight by including organic acid testing, which evaluates potential nutritional deficiencies, oxidative stress, gut dysbiosis, melatonin levels, and neuroinflammation.
With the DUTCH Plus®, providers also get a closer look into adrenal function with details about a patient’s cortisol awakening response (CAR) by showing cortisol's natural rise and fall within the first hour of waking.
10 business days
Preparation & Timing
- DO NOT collect your sample if you are traveling for short periods of time.
- Some supplements may affect your organic acid results. Please consult your healthcare provider regarding collection preparation and timing if you take any of the following supplements:
- Tyrosine
- L-Dopa
- D,L-Phenylalanine (DLPA)
- Mucuna
- Quercetin
- DO NOT skip doses of birth control unless instructed by your healthcare provider.
- If you are taking any of the following hormones, continue using them as directed.
- Topical hormones
- Oral progesterone (take at night)
- If you are taking any of the following medications, collect your sample halfway between doses.
- Patch hormones
- Pellet hormones
- Injectable hormones
- If you are taking any of the following medications, please consult your healthcare provider for collection timing.
- Sublingual hormones
- Oral hydrocortisone
- Glucocorticoids
- Men and menopausal women can collect their samples at any time.
- Cycling women should take the test according to the following schedule:
- Irregular cycles: Watch THIS video to determine when to collect.
- Regular cycles: Use the table below to determine when to collect your sample.
- You should begin collecting your sample 6-9 days before your cycle ends.
72 hours before sample collection
- Avoid taking the following hormones until you have finished sample collection.
- Oral or sublingual DHEA
- Oral or sublingual estrogen
- Oral or sublingual pregnenolone
48 hours before sample collection
- Avoid the following foods and supplements until you have finished sample collection.
- Bananas
- Creatine
- Fava beans
24 hours before sample collection
- Avoid alcohol until you have finished sample collection.
Day of sample collection
- Limit your fluid intake.
- Keep fluids to no more than 40 oz total (spread evenly throughout the day).
- DO NOT drink more than 8 oz of caffeine.
- DO NOT eat or drink until after collection 3.
- DO NOT brush your teeth in the morning until after collection 3.
- DO NOT brush your teeth in the evening until after collection 6.
Minimum age:
9
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
