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Genova Diagnostics

Endo+: Melatonin

Genova Diagnostics

Sample type: Saliva

Requires fasting: No

At home test


Details

Endo+ provides a tailored hormonal testing approach that reveals the complex interplay of thyroid, adrenal, melatonin, and sex hormones. This panel assesses diurnal melatonin patterns.


  • Melatonin Evening
  • Melatonin Morning
  • Melatonin Night

Estimated days for results: Results should arrive 21 business days after the lab receives samples.


21 business days


View here

  • Add-On: Androstenedione
  • Add-On: Endo+ Adrenocortex
  • Add-On: Endo+ Salivary Hormones
  • Add-On: Endo+ Serum Hormones
  • Add-On: Endo+ Thyroid Hormones
  • Add-On: Endo+ Urine Estrogens
  • Add-On: Follicle-Stimulating Hormone (FSH)
  • Add-On: Genomic SNP - COMT (V158M)
  • Add-On: Genomic SNP - CYP1B1
  • Add-On: Genomic SNP - MTHFR Combined (C677T & A1298C)
  • Add-On: Genomic SNP - VDR
  • Add-On: Luteinizing Hormone (LH)

Before You Start
  • Please read the test collection instructions carefully.
  • You will collect three saliva samples on one day.
  • If you are a male or a menopausal female, you may collect on any day.
  • If you are a premenopausal female, collect your sample between day 19 and day 25 of your menstrual cycle. (Day 1 is the first day of your period.)
  • You do not need to discontinue any medications unless directed by your healthcare provider.

Day of Collection
  • If you are taking hormone medications, wait to take your medication until after you have collected your first sample.
  • Avoid the following activities for 1 hour before collecting your saliva samples: 
    • Eating
    • Brushing your teeth
    • Flossing your teeth
    • Using mouthwash
    • Using lip balm
    • Chewing gum
    • Using tobacco products

Urine Add-On
  • 24 Hours Before Collection 
    • Drink no more than 48 oz of fluid.
  • Day of Collection 
    • You will collect your first urination of the day.
    • If you wake to urinate during the night, within 6 hours of when you typically wake for the day, collect your urine in the cup, refrigerate, and then combine with your first morning urine.

Swab Add-On
  • If you are collecting a swab add-on, collect immediately upon waking.

Serum Add-Ons
  • Sample collection must be performed by a phlebotomist.
  • You must fast for 12 hours before your blood draw. 
    • Fasting before a blood draw means you don't eat or drink anything except water. 
    • Your doctor should provide any special instructions related to fasting for your test. Always follow your doctor's instructions.
  • Freeze the provided freezer brick for at least 8 hours before your blood draw.

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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