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Genova Diagnostics

SIBO - 2 Hour

Genova Diagnostics

Sample type: Breath

Requires fasting: Yes

At home test


Details

When it comes to gastrointestinal symptoms, studies have shown that a large percentage of Irritable Bowel Syndrome (IBS) is actually Small Intestinal Bacterial Overgrowth (SIBO). SIBO is a common clinical condition characterized by excessive bacterial development in the small intestine. This non-invasive breath test captures exhaled hydrogen and methane, to provide practitioners with the insight to better differentiate and diagnose SIBO.


  • Hydrogen, Pre-Dose Lactulose
  • Hydrogen, 20M Post-Dose Lactulose
  • Hydrogen, 40M Post-Dose Lactulose
  • Hydrogen, 1H Post-Dose Lactulose
  • Hydrogen, 1.5H Post-Dose Lactulose
  • Hydrogen, 2H Post-Dose Lactulose
  • Methane, Pre-Dose Lactulose
  • Methane, 20M Post-Dose Lactulose
  • Methane, 40M Post-Dose Lactulose
  • Methane, 1H Post-Dose Lactulose
  • Methane, 1.5H Post-Dose Lactulose
  • Methane, 2H Post-Dose Lactulose

Estimated days for results: Results should arrive 10 business days after the lab receives samples.

Why choose Genova Diagnostics' Gut Health Products?
Studies show that a large percentage of Irritable Bowel Syndrome (IBS) is actually Small Intestinal Bacterial Overgrowth (SIBO). Experts suggest non-invasive breath testing for the diagnosis of SIBO. 

Genova’s SIBO profiles utilize the North American Consensus Guidelines published in the American Journal of Gastroenterology. Genova’s SIBO Profiles are non-invasive breath tests which capture exhaled hydrogen (H2) and methane (CH4) gases following patient ingestion of a Lactulose ℞ solution to evaluate small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO). 

Clinicians have the option of a 2 or 3-hour SIBO assessment. 

Symptoms and conditions commonly associated with SIBO include: 
  • Bloating/distension 
  • Gas Diarrhea 
  • Constipation 
  • Abdominal pain 
  • Dyspepsia 
  • Irritable Bowel Syndrome (IBS) 
  • Inflammatory Bowel Disease (IBD) 
  • Celiac 
  • Disease 
  • Diabetes 
  • Fibromyalgia 
  • Rosacea 
  • Parkinson’s Disease 
  • Obesity 

Risk factors for development of SIBO include:
  • Intestinal motility disorders 
  • Chronic pancreatitis 
  • Abdominal structural/anatomic issues 
  • Gastroenteritis Immunocompromise 

Decreased bacteriostatic digestive secretions (HCl, pancreatic enzymes, bile acids) such as with PPI use Ileocecal valve dysfunction If left untreated, SIBO can lead to complications such as malabsorption and intestinal permeability, or leaky gut.

10 business days


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Considerations

• Do not use if you are allergic to lactulose or on a galactose/ lactose restricted diet. Diabetics should proceed with caution.
• Do not collect during acute infectious illness.
• If you weigh less than 100 pounds, follow instructions printed on the blue bag.
• Do not use for children under 25 pounds.

Preparation & Timing 

Plan to collect early in the workweek and ship within 2 days of collection. 
Wait 4 weeks from your last colonoscopy or barium enema. 
Wait 2-4 weeks from your last dose of antibiotics, antifungals, Pepto-Bismol®, or herbal/natural antimicrobial products. 

7 days before collection do not use laxatives, stool softeners, stool bulking agents, antacids containing aluminum, or magnesium hydroxide. 

24 hours before collection limit diet to only: meat/poultry/fish/seafood that is not cured or brined, plain steamed white rice, eggs, clear meat broth (no bone/ cartilage or vegetables), fats/oils (coconut, olive, vegetable oils, butter, or lard), salt and pepper (no other herbs/spices), weak black coffee and/or weak black tea (no sweeteners or cream, no green or herbal teas), plain water (no mineral water or water with additives) Do not take probiotics. 

12 hours before and during collection do not eat or drink anything other than water. 

Do not take non-essential medications or supplements unless your doctor has advised you otherwise. Do not chew gum, eat candy, or use mouthwash or toothpaste. 

1 hour before and during collection do not smoke or inhale second-hand smoke. Do not sleep or exercise. Do not eat or drink anything during the collection. 

Water is okay after collecting Tube 5.

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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