GI 360 Profile
Mosaic Diagnostics
Sample type: Stool
Requires fasting: No
At home test
Details
The GI 360 Profile is an innovative, comprehensive, and clinically applicable stool profile, utilizing multiplex PCR molecular technology coupled with growth-based culture and ID by MALDI-TOF, sensitive biochemical assays and microscopy to detect and assess the status of pathogens, viruses, parasites and bacteria that may be contributing to acute or chronic gastrointestinal symptoms and disease.
- Prevotella spp.
- Veillonella spp.
- Fasciola hepatica
- Fasciolopsis buski
- Hookworm
- Yeast Culture
- Taenia spp.
- Chilomastix mesnili
- Entamoeba hartmanni
- Iodamoeba buetschlii
- Entamoeba polecki
- Blastocystis spp.
- Balantidium coli
- Hymenolepis nana
- Hymenolepis diminuta
- Dipylidium caninum
- Diphyllobothrium latum
- Butyrate
- Pancreatic Elastase 1
- Strongyloides stercoralis
- Enterobius vermicularis
- Capillaria philippinensis
- Red Blood Cells, Stool
- White Blood Cells, Stool
- Faecalibacterium prausnitzii
- Akkermansia muciniphila
- Cryptosporidium spp.
- Giardia
- Lactobacillus spp.
- Bifidobacterium spp.
- Beta-Glucuronidase
- Trichuris trichiura
- Entamoeba coli
- Endolimax nana
- Dientamoeba fragilis
- Ascaris lumbricoides
- Escherichia spp.
- Campylobacter spp.
- Salmonella spp.
- Streptococcus spp.
- Firmicutes
- Vibrio cholerae
- Secretory IgA
- Pentatrichomonas hominis
- Norovirus GI/GII
- Entamoeba histolytica
- Adenovirus 40/41
- Citrobacter freundii
- Bacteroides fragilis
- Lactoferrin, Stool [Mass/Volume]
- Lysozyme
- Acetate
- Carbohydrates
- Propionate
- Valerate
- Muscle fibers
- Mucus
- Vegetable fibers
- Cystoisospora belli
- Pollen
- Charcot-leyden crystals
- Paragonimus westermani
- Heterophyes heterophyes
- Clonorchis sinensis
- Capillaria hepatica
- Retortamonas intestinalis
- Enteromonas hominis
- Rotavirus A
- Actinobacteria
- Actinomycetales
- Alistipes onderdonkii
- Alistipes spp.
- Bacilli class
- Bacteroides spp.
- Bacteroides stercoris
- Bacteroides zoogleoformans
- Catenibacterium mitsuokai
- Dialister invisus
- Dorea spp.
- Eubacterium biforme
- Eubacterium hallii
- Eubacterium rectale
- Eubacterium siraeum
- Lachnospiraceae
- Mycoplasma hominis
- Parabacteroides johnsonii
- Phascolarctobacterium spp.
- Proteobacteria
- Ruminococcus gnavus
- Parabacteroides spp.
- Ruminococcus bromii
- beta-Hemolytic Streptococci, Group B
- gamma-Hemolytic Streptococci
- Yersinia spp.
- Vibrio spp.
- Aeromonas spp.
- Enterobacter cloacae
- Comamonas jiangduensis
- Plesiomonas shigelloides
- Edwardsiella tarda
- Streptococcus agalactiae
- Ruminococcus albus
- Pediococcus acidilactici
- Lactobacillus ruminis
- Megasphaera micronuciformis
- Shigella spp.
- Clostridioides difficile
- Total Short-Chain Fatty Acids
- Escherichia coli
- Entamoeba dispar
- Calprotectin, Stool
- Occult Blood, Stool
- pH, Stool
- Fat Stain
- Clostridia Class
- Clostridium L2-50
- Dysbiosis Index
- Streptococcus thermophilus
- Streptococcus sanguinis
Estimated days for results: Results should arrive 10 business days after the lab receives samples.
The GI360™ Stool Profile offers an extensive assessment of the gastrointestinal microbiome. It includes:
- PCR Analysis for the Abundance and Diversity of Key Bacterial Populations of the GI Microbiome
- PCR Detection of Pathogenic Bacteria, Viruses, and Parasites
- Comprehensive Parasitology by Microscopy
- MALDI-TOF ID of Cultured Bacteria and Yeast
- Broad Range of Stool Chemistry Markers
- Standardized Susceptibility Testing of Isolated Bacteria and Yeast
Microbiome Abundance and Diversity:
The GI360 Profile is a gut microbiota DNA analysis tool that identifies and characterizes the abundance and diversity of more than 45 targeted analytes that peer-reviewed research has shown to contribute to dysbiosis and other chronic disease states.
The GI360 Profile can identify the presence of pathogenic viruses, bacteria, and parasites using multiplexed, real-time PCR. Viruses are the primary cause of acute diarrhea, and the least commonly tested. The identification of pathogenic bacteria, viruses, and parasites improves treatment strategies and patient outcomes.
The Dysbiosis and Diversity Index:
These indices are calculated from the results of the Microbiome Profile, with scores ranging from 1 to 5, and do not include consideration of dysbiotic and pathogenic bacteria, yeast, parasites, and viruses that may be reported in subsequent sections of the GI360 Profile.
A dysbiosis score above 2 indicates dysbiosis; a microbiota profile that differs from the defined normobiotic reference population. The higher the score above 2, the more the sample deviates from the normobiotic profile.
A diversity score of 3 indicates an expected amount of diversity, with 4 & 5 indicating an increased distribution of bacteria based on the number of different species and their abundance in the sample, calculated based on Shannon’s diversity index. Scores of 1 or 2 indicate less diversity than the defined normobiotic reference population.
This expanded view of clinically significant bacteria offers actionable data to the practitioner, particularly in combination with the complementary methodologies employed in the GI360™ Profile.
10 business days
Before You Start
- Follow the test collection instructions here.
- You will collect samples on one, two, or three separate days. Your healthcare provider will tell you how many days to collect.
- Samples must be collected at least 12 hours apart.
- Samples must be shipped within 5 days of the second collection.
- Ship your samples Monday - Wednesday only.
- It is best to start your collection over the weekend so you can ship on time.
- DO NOT collect your samples while menstruating or actively bleeding from hemorrhoids.
4 Weeks Before Collection
- Avoid the following procedures.
- Colonoscopy
- Barium enema
2 Weeks Before Collection
- Avoid the following medications. DO NOT discontinue any prescription medications without first consulting your healthcare provider.
- Antibiotics
- Antiparasitics
- Antifungals
- Probiotic supplements
- Proton pump inhibitors (PPI)
- Bismuth
48 Hours Before Collection
- Avoid the following foods and medications. DO NOT discontinue any prescription medications without first consulting your healthcare provider.
- Digestive enzymes
- Antacids
- Iron supplements
- Over 250 mg daily of Vitamin C
- Aspirin or other NSAIDs
- Activated charcoal
- Bentonite clay
- Betaine HCl
- Mineral oil
- Castor oil
- Glycerin-based laxatives, enemas, or suppositories
24 Hours Before Collection
- DO NOT use suppositories or mineral oil before sample collection.
- If you have trouble producing stool, you may use one of the following:
- Oral phosphate soda laxatives (e.g., Fleet)
- Magnesium citrate
- Psyllium fiber
- Enemas using distilled water only
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
