Organic Acids (OAT)
Mosaic Diagnostics
Sample type: Urine
Requires fasting: No
At home test
Details
The Organic Acids Test (OAT) provides a comprehensive metabolic analysis of a patient's overall health, including intestinal yeast and bacteria, vitamin and mineral levels, oxidative stress, neurotransmitter levels, and oxalates.
- Lactic Acid
- Malic Acid
- Succinic Acid
- Suberic Acid
- Pyruvic Acid
- Oxalic Acid
- Orotic Acid
- Citric Acid
- Adipic Acid
- Glutaric Acid
- Quinolinic Acid
- 3-Hydroxybutyric Acid
- 2-Hydroxybutyric Acid
- 3-Indoleacetic Acid
- 4-Hydroxyphenylacetic Acid
- Hippuric Acid
- Tartaric Acid
- 5-Hydroxyindoleacetic Acid
- Vanillylmandelic Acid
- Pyroglutamic Acid
- Kynurenic Acid
- Homovanillic Acid
- Sebacic acid
- Homogentisic acid
- Mandelic acid
- Pyridoxic Acid
- Methylsuccinic acid
- Ethylmalonic acid
- Fumaric acid
- 4-Hydroxybenzoic acid
- 2-Hydroxyhippuric Acid
- 2-Hydroxyisocaproic Acid
- 2-Hydroxyisovaleric Acid
- 2-Hydroxyphenylacetic Acid
- 2-Oxo-4-methiolbutyric Acid
- 2-Oxoglutaric Acid
- 2-Oxoisocaproic Acid
- 2-Oxoisovaleric Acid
- 3-(3-hydroxyphenyl)-3-hydroxypropionic Acid
- 3-Hydroxyglutaric Acid
- 3-Methyl-2-oxovaleric Acid
- 3-Methylglutaconic Acid
- 3-Methylglutaric Acid
- 3-OH-3-Methylglutaric Acid
- 3-Oxoglutaric Acid
- 4-Cresol
- 4-Hydroxybutyric Acid
- 4-Hydroxyhippuric Acid
- 4-Hydroxyphenyllactic Acid
- 5-Hydroxymethyl-2-furoic Acid
- Acetoacetic Acid
- Aconitic Acid
- Arabinose
- Ascorbic Acid
- Carboxycitric Acid
- Citramalic Acid
- Dihydroxyphenylacetic Acid
- Dihydroxyphenylpropionic Acid
- Furan-2,5-dicarboxylic Acid
- Furancarbonylglycine
- Glyceric Acid
- Glycolic Acid
- HVA/DOPAC Ratio
- HVA/VMA Ratio
- Malonic Acid
- Methylcitric Acid
- N-Acetylaspartic Acid
- N-Acetyl Cysteine
- Pantothenic Acid
- Phenyllactic Acid
- Phenylpyruvic Acid
- Phosphoric Acid
- Thymine
- Tricarballylic Acid
- Uracil
- Methylmalonic Acid (MMA), Urine
Estimated days for results: Results should arrive 10 business days after the lab receives samples.
Organic acids are products of the body’s metabolic pathways. Evaluation of these downstream metabolites from various metabolic pathways provides insight into important areas related to gut health, mitochondrial dysfunction, neurotransmitter status, indicators of detoxification and macronutrient breakdown, and nutritional status. This makes organic acid testing a valuable tool to assess the functional need for essential nutrients, diet modification, antioxidant protection, detoxification, and other therapies.
The Organic Acids Test (OAT) provides a comprehensive nutritional and metabolic snapshot of an individual’s overall health. The OAT measures 76 organic acids from one easy-to-collect urine sample.
Why Run an Organic Acids Test (OAT)?
The Organic Acids Test (OAT) is a simple and efficient way to assess a number of metabolic pathways, providing insight into imbalances and nutrient needs. The OAT can provide insight into a wide range of conditions, making it valuable for individuals who are experiencing complex chronic conditions.
The OAT test report is organized into clinically useful categories, including:
- Intestinal Microbial Overgrowth markers evaluate for candida activity, clostridia bacteria toxins, potential mold exposure, and imbalance in the gut microflora.
- Oxalate Metabolites provide insight into oxalate levels being generated by organisms within the system or via dietary contributions.
- Glycolytic Cycle Metabolites and Mitochondrial Markers (Krebs Cycle and Amino Acid Metabolites) evaluate for metabolic efficiency (e.g., use of glucose and amino acids for energy generation) and mitochondrial dysfunction.
- Neurotransmitter Metabolites evaluate for phenylalanine, tyrosine, and tryptophan metabolism, which are linked to neurotransmitter status and quinolinic acid production.
- Pyrimidine Metabolites & Ketone and Fatty Acid Oxidation markers give insight into folate status and cellular turnover, as well as mitochondrial utilization of fatty acids for energy production.
- Nutritional Markers provide insight into the sufficiency of essential vitamins, antioxidants, and metabolic pathway cofactors.
- Indicators of Detoxification assess for the presence of oxidative stress via markers of glutathione sufficiency and methylation versus transsulfuration function.
- Amino Acid Metabolites may suggest functional nutrient need or be reflective of genetic metabolic dysfunction if a consistently, persistently elevated level of a particular analyte is noted.
- The Mineral Metabolism marker provides insight into dietary intake of phosphate and can give insights into Vitamin D levels.
10 business days
Before You Start
- Follow the test collection instructions here.
- DO NOT collect your sample while menstruating.
- If you are taking antibiotics, finish the course of medication and wait 48 hours before collecting your sample.
- Ship your sample Monday - Thursday only.
48 Hours Before Collection
- Avoid the following foods and supplements.
- Apples and apple juice
- Grapes (including raisins) and grape juice
- Pears and pear juice
- Cranberries and cranberry juice
- Echinacea
- Reishi mushrooms
- Arabinogalactan
- Ribose supplements
Day of Collection
- Collect your sample upon waking.
- DO NOT eat or drink before collecting your sample.
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
