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Quest Diagnostics

17-Hydroxyprogesterone

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

This test is crucial for diagnosing Congenital Adrenal Hyperplasia (CAH), a condition where the body has low cortisol levels but high ACTH levels. It's also used to monitor cortisol replacement therapies, investigate causes of infertility, and check for adrenal and ovarian tumors.


  • 17-hydroxyprogesterone, Serum

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

17-Hydroxyprogesterone
This test is crucial for diagnosing Congenital Adrenal Hyperplasia (CAH), a condition where the body has low cortisol levels but high ACTH levels. It's also used to monitor cortisol replacement therapies, investigate causes of infertility, and check for adrenal and ovarian tumors.

What patients is this test right for?
This test is particularly important for individuals suspected of having CAH, experiencing infertility issues, or being monitored for cortisol therapy effectiveness.

What type of sample is required for this test?
0.5 mL serum collected in a red-top tube (no gel) is needed for this test.

Test Resources
Resources for this test are currently being updated.


3–6 business days


Adult Males
18-30 years                     32-307 ng/dL
31-40 years                     42-196 ng/dL
41-50 years                     33-195 ng/dL
51-60 years                     37-129 ng/dL

Adult Females
Pre-Menopausal Mid Follicular   23-102 ng/dL
Pre-Menopausal Surge            67-349 ng/dL
Pre-Menopausal Mid Luteal       139-431 ng/dL
Postmenopausal Phase            ≤45 ng/dL

Pregnancy
First Trimester                 78-457 ng/dL
Second Trimester                90-357 ng/dL
Third Trimester                 144-578 ng/dL

Male and Female
<30 days                        Not established
1-11 months                     ≤147 ng/dL
1 year                          ≤139 ng/dL
2 years                         ≤134 ng/dL
3 years                         ≤131 ng/dL
4 years                         ≤131 ng/dL
5 years                         ≤133 ng/dL
6 years                         ≤137 ng/dL
7 years                         ≤145 ng/dL
8 years                         ≤154 ng/dL
9 years                         ≤166 ng/dL
10 years                        ≤180 ng/dL
11 years                        ≤196 ng/dL
12 years                        ≤213 ng/dL
13 years                        ≤233 ng/dL
14 years                        ≤254 ng/dL
15 years                        19-276 ng/dL
16 years                        23-300 ng/dL
17 years                        26-325 ng/dL

Tanner Stages
II-III Males                    12-130 ng/dL
II-III Females                  18-220 ng/dL
IV-V Males                      51-190 ng/dL
IV-V Females                    36-200 ng/dL

  • Hormones
  • Adrenals and stress

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 0.5 mL serum collected in a red-top tube (no gel) 
  • Alternative: NA 
  • Minimum Volume: 0.25 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Refrigerated (Cold Packs) 
  • Specimen Stability
    • Room temperature: 48 hours 
    • Refrigerated: 7 days 
    • Frozen: 2 years 
  • Reject Criteria
    • Gross hemolysis • Serum separator tube (SST) 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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