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Quest Diagnostics

Activated Protein C-Resistance

Quest Diagnostics

Sample type: Plasma

Requires fasting: No

Phlebotomy required


Details

Activated Protein C-Resistance - Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma-based functional test for the determination of APC resistance caused by the factor V Leiden mutation.


  • Activated Protein C Resistance

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Details
Activated Protein C-Resistance - Activated protein C (APC) resistance is the most frequent hereditary defect associated with deep vein thrombosis. Over 95% of the APC resistance phenotype is due to the Factor V Leiden mutation. The APC-Resistance assay is a plasma-based functional test for the determination of APC resistance caused by the factor V Leiden mutation.

What type of sample is required for this test?
2 mL frozen platelet-poor citrated plasma collected in a 3.2% sodium citrate (light-blue-top) tube

Test Resources
For more information, please consult your healthcare provider.


2–5 business days


≥2.1 Ratio

  • Cardiovascular

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 2 mL frozen platelet-poor citrated plasma collected in a 3.2% sodium citrate (light-blue-top) tube 
  • Alternative: NA 
  • Minimum Volume: 1 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Frozen 
  • Specimen Stability
    • Frozen: 60 days 
  • Reject Criteria
    • Gross hemolysis • Clotted specimen • Serum 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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