Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS
Quest Diagnostics
Sample type: Plasma
Requires fasting: No
Phlebotomy required
Details
Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS - The Aldosterone-renin ratio is used to screen for primary aldosteronism.
- ALDO/PRA Ratio
- Aldosterone, LC/MS/MS
- Plasma Renin Activity, LC/MS/MS
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
Details
Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS - The Aldosterone-renin ratio is used to screen for primary aldosteronism.
What type of sample is required for this test?
1.8 mL frozen plasma collected in an EDTA (lavender-top) tube
Test Resources
For more information, please consult your healthcare provider.
2–5 business days
Aldosterone
Adult
Upright 8:00–10:00 AM ≤28 ng/dL
Upright 4:00–6:00 PM ≤21 ng/dL
Supine 8:00–10:00 AM 3–16 ng/dL
Pediatric
1–12 months** 2–70 ng/dL
1–4 years** 2–37 ng/dL
5–9 years ≤9 ng/dL
10–13 years ≤21 ng/dL
14–17 years ≤35 ng/dL
Infants
Premature (31–35 weeks)** ≤144 ng/dL
Term** ≤217 ng/dL
Tanner Stages**
II–III Males 1–13 ng/dL
II–III Females 2–20 ng/dL
IV–V Males 3–14 ng/dL
IV–V Females 4–32 ng/dL
**Pediatric data from J Clin Endocrinol Metab. 1992;75:1491 and J Clin Endocrinol Metab. 1989;69:1133–1136.
Plasma Renin Activity 0.25–5.82 ng/mL/h
Aldosterone/PRA Ratio 0.9–28.9 Ratio
Adult
Upright 8:00–10:00 AM ≤28 ng/dL
Upright 4:00–6:00 PM ≤21 ng/dL
Supine 8:00–10:00 AM 3–16 ng/dL
Pediatric
1–12 months** 2–70 ng/dL
1–4 years** 2–37 ng/dL
5–9 years ≤9 ng/dL
10–13 years ≤21 ng/dL
14–17 years ≤35 ng/dL
Infants
Premature (31–35 weeks)** ≤144 ng/dL
Term** ≤217 ng/dL
Tanner Stages**
II–III Males 1–13 ng/dL
II–III Females 2–20 ng/dL
IV–V Males 3–14 ng/dL
IV–V Females 4–32 ng/dL
**Pediatric data from J Clin Endocrinol Metab. 1992;75:1491 and J Clin Endocrinol Metab. 1989;69:1133–1136.
Plasma Renin Activity 0.25–5.82 ng/mL/h
Aldosterone/PRA Ratio 0.9–28.9 Ratio
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
Specimen
- Preferred Specimen(s): 1.8 mL frozen plasma collected in an EDTA (lavender-top) tube
- Alternative: NA
- Minimum Volume: 0.8 mL
- Collection Instructions: NA
Storage and shipping instructions
- Transport Container: Transport tube
- Transport Temperature: Frozen
- Specimen Stability:
- Room temperature: 24 hours
- Refrigerated: 24 hours
- Frozen: 28 days
- Reject Criteria:
- Moderate to gross hemolysis • Plasma collected in a plasma separator tube • Received thawed
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
