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Quest Diagnostics

ANAlyzeR™ ANA, IFA with Reflex Titer/Pattern, Systemic Autoimmune Panel 1

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

ANAlyzeR™ ANA, IFA with Reflex Titer/Pattern, Systemic Autoimmune Panel 1 - This panel can be helpful in the diagnosis of systemic rheumatic disorders and other autoimmune diseases. Although the test for antinuclear antibodies (ANA) is strongly associated with systemic lupus erythematosus (SLE), the laboratory evaluation for individuals with clinical suspicion of a variety of autoimmune diseases often begins with an ANA screen. This panel simultaneously tests for ANA (using immunofluorescence) as well as the important specific autoantibodies associated with a positive ANA. It also includes testing for complement proteins, rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, polymyositis, anti-phospholipid antibody syndrome, and autoimmune thyroid disease.


Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.


Initial test
  • Centromere b antibody
  • Jo-1 antibody
  • Sjogren's antibody (ss-a)
  • Sjogren's antibody (ss-b)
  • Antinuclear Antibodies Screen (IFA)
  • Beta-2-Glycoprotein I Antibody (IgA)
  • Beta-2-Glycoprotein I Antibody (IgG)
  • Beta-2-Glycoprotein I Antibody (IgM)
  • Cardiolipin Antibody (IgA)
  • Cardiolipin Antibody (IgG)
  • Cardiolipin Antibody (IgM)
  • Chromatin (Nucleosomal) Antibody
  • Complement Component C3c
  • Complement Component C4c
  • Cyclic Citrullinated Peptide (CCP) Antibody (IgG)
  • DNA (ds) Antibody, Crithidia IFA
  • Mutated Citrullinated Vimentin (MCV) Antibody
  • Rheumatoid Factor (IgA)
  • Rheumatoid Factor (IgG)
  • Rheumatoid Factor (IgM)
  • RNP Antibody
  • Scleroderma (Scl-70) Antibody
  • Sm Antibody
  • Sm/RNP Antibody
  • Thyroid Peroxidase Antibodies (TPO)
Possible reflex biomarkers
  • ANA Titer
  • ANA Pattern
  • DNA (ds) Antibody Titer, Crithidia

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Details

ANAlyzeR™ ANA, IFA with Reflex Titer/Pattern, Systemic Autoimmune Panel 1 - This panel can be helpful in the diagnosis of systemic rheumatic disorders and other autoimmune diseases. Although the test for antinuclear antibodies (ANA) is strongly associated with systemic lupus erythematosus (SLE), the laboratory evaluation for individuals with clinical suspicion of a variety of autoimmune diseases often begins with an ANA screen. This panel simultaneously tests for ANA (using immunofluorescence) as well as the important specific autoantibodies associated with a positive ANA. It also includes testing for complement proteins, rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, polymyositis, anti-phospholipid antibody syndrome, and autoimmune thyroid disease.

Resources

2–5 business days


  • Autoimmune

Fasting for overnight before your blood draw is preferred but not required.
  • Fasting before a blood draw means you don't eat or drink anything except water. 
  • Your doctor should provide any special instructions related to fasting for your test. Always follow your doctor's instructions.

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 9 mL serum 
  • Alternative: NA 
  • Minimum Volume: 6 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Refrigerated (Cold Packs) 
  • Specimen Stability
    • Refrigerated: 7 days 
    • Frozen: 8 days 
  • Reject Criteria: NA 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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