
Chromatin (Nucleosomal) Antibody
Quest Diagnostics
Sample type: Serum
Requires fasting: No
Phlebotomy required
Details
Chromatin (Nucleosomal) Antibody - This test is crucial for understanding the autoimmune response in systemic lupus erythematosus (SLE), a condition where the body's immune system mistakenly attacks its own tissues. About 90% of people with SLE show positive results for this test, indicating their immune system is reacting to nucleosomes, which are components of the cell's nucleus.
- Chromatin (Nucleosomal) Antibody
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
This test is crucial for understanding the autoimmune response in systemic lupus erythematosus (SLE), a condition where the body's immune system mistakenly attacks its own tissues. About 90% of people with SLE show positive results for this test, indicating their immune system is reacting to nucleosomes, which are components of the cell's nucleus.
Symptoms of SLE can vary widely but often include:
- Joint pain and swelling
- Skin rashes, particularly those that worsen with sun exposure
- Fatigue
- Fever
- Chest pain when breathing deeply
- Headaches, confusion, and memory loss
2–5 business days
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 1 mL serum
- Alternative: NA
- Minimum Volume: 0.5 mL
- Collection Instructions: NA
- Transport Container: Transport tube
- Transport Temperature: Room Temperature
- Specimen Stability:
- Room temperature: 4 days
- Refrigerated: 7 days
- Frozen: 30 days
- Reject Criteria:
- Gross hemolysis • Grossly lipemic • Grossly icteric
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island




