Comprehensive Hereditary Cancer Panel
Quest Diagnostics
Sample type: Whole blood
Requires fasting: No
Phlebotomy required
Details
This test is particularly important for individuals with a family history of cancer, as it can help identify inherited cancer risks.
- Apc
- Atm
- Axin2
- Bard1
- Bmpr1a
- Brca1
- Brca2
- Brip1
- Cdh1
- Cdk4
- CDKN2A (p16, p14)
- Chek2
- Epcam
- Grem1
- Hoxb13
- Mlh1
- Msh2
- Msh3
- Msh6
- Mutyh
- Nf1
- Nthl1
- Palb2
- Pms2
- Pold1
- Pole
- Pten
- Rad51c
- Rad51d
- Smad4
- Stk11
- Tp53
- Fh
- Max
- Men1
- Ret
- Sdha
- Sdhaf2
- Sdhb
- Sdhc
- Sdhd
- Tmem127
- Vhl
- Bap1
- Blm
- Cdkn1b
- Dicer1
- Fanca
- Fancc
- Fancm
- Flcn
- Galnt12
- Met
- Mitf
- Mre11 (mre11a)
- Nbn
- Pot1
- Ptch1
- Rad50
- Recql
- Smarca4
- Sufu
- Tsc1
- Tsc2
- Xrcc2
- EGFR
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
Details
The Comprehensive Hereditary Cancer Panel tests for 66 genes linked to a wide range of hereditary cancers. This includes cancers that may affect the breast, colon, endometrium, stomach, urinary tract, ovary, pancreas, prostate, rectum, neuroendocrine system, thyroid, adrenal glands, paraganglia, and other tissues. If the test finds a pathogenic or likely pathogenic variant, it means there's an increased risk of developing certain cancers compared to the general population.
Who should consider this test?
This test is particularly important for individuals with a family history of cancer, as it can help identify inherited cancer risks. Knowing your genetic risk can guide future monitoring and prevention strategies.
What type of sample is required for this test?
5 mL of whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube. A simple blood draw is needed.
Test Resources http://education.questdiagnostics.com/faq/FAQ217
2–5 business days
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
Specimen
- Preferred Specimen(s): 5 mL whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube
- Alternative: NA
- Minimum Volume: 2 mL
- Collection Instructions: NA
Storage and shipping instructions
- Transport Container: EDTA (lavender-top) tube
- Transport Temperature: Room Temperature
- Specimen Stability:
- Room temperature: 14 days
- Refrigerated: 14 days
- Reject Criteria: NA
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
