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Quest Diagnostics

Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

The Cyclic Citrullinated Peptide (CCP) Antibody (IgG) Test is a specialized test that helps in the diagnosis of Rheumatoid Arthritis (RA). It detects the presence of specific antibodies (CCP IgG) in the blood, which are more common in people with RA compared to other conditions like hepatitis C. This test is part of the criteria used to classify Rheumatoid Arthritis, along with other tests such as rheumatoid factor, C-reactive protein, and erythrocyte sedimentation rate (ESR). About 70% of RA patients test positive for Anti-CCP IgG, making it a crucial marker for the disease, whereas it's rarely found in healthy individuals or those with other diseases.


  • Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Cyclic Citrullinated Peptide (CCP) Antibody (IgG)
This test is a specialized test that helps in the diagnosis of Rheumatoid Arthritis (RA). It detects the presence of specific antibodies (CCP IgG) in the blood, which are more common in people with RA compared to other conditions like hepatitis C. This test is part of the criteria used to classify Rheumatoid Arthritis, along with other tests such as rheumatoid factor, C-reactive protein, and erythrocyte sedimentation rate (ESR). About 70% of RA patients test positive for Anti-CCP IgG, making it a crucial marker for the disease, whereas it's rarely found in healthy individuals or those with other diseases.

What patients is this test right for?
This test is particularly useful for individuals suspected of having Rheumatoid Arthritis, especially when symptoms like joint pain, stiffness, and swelling are present.

What type of sample is required for this test?
1 mL serum.

Test Resources
Resources are not provided for this test.


3–5 business days


Negative         <20 Units
 Weak positive    20-39 Units
 Moderate positive40-59 Units
Strong positive  >59 Units


  • Autoimmune

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 1 mL serum 
  • Alternative: NA 
  • Minimum Volume: 0.5 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Room Temperature 
  • Specimen Stability
    • Room temperature: 4 days 
    • Refrigerated: 7 days 
    • Frozen: 30 days 
  • Reject Criteria
    • Gross hemolysis • Grossly lipemic • Plasma 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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