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Quest Diagnostics

Cytomegalovirus Antibodies (IgG, IgM)

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

Cytomegalovirus Antibodies (IgG, IgM) - Intrauterine or congenital CMV infections occur in 0.5 to 2.2% of all live births. Symptomatic congenital infections usually occur in infants born to non-immune mothers who have primary infections during pregnancy. Latency and reactivation of CMV influence the interpretation of serological results. A single positive CMV IgG result is and indication of present or past infection. The presence of CMV IgM suggests a recent CMV exposure but does not differentiate between primary infection and reactivation.


  • Cytomegalovirus antibody (igg)
  • Cytomegalovirus antibody (igm)

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Details
Cytomegalovirus Antibodies (IgG, IgM) - Intrauterine or congenital CMV infections occur in 0.5 to 2.2% of all live births. Symptomatic congenital infections usually occur in infants born to non-immune mothers who have primary infections during pregnancy. Latency and reactivation of CMV influence the interpretation of serological results. A single positive CMV IgG result is and indication of present or past infection. The presence of CMV IgM suggests a recent CMV exposure but does not differentiate between primary infection and reactivation.

What type of sample is required for this test?
1.5 mL serum

Test Resources
For more information, please consult your healthcare provider.


3–4 business days


Cytomegalovirus Antibody (IgG)
  U/mL                     Interpretation
  <0.60                     Negative
  0.60–0.69             Equivocal
  ≥0.70                     Positive

A positive result indicates that the patient has antibody to CMV. It does not differentiate between an active or past infection.

Cytomegalovirus Antibody (IgM)
  AU/mL                 Interpretation
  <30.00                 No antibody detected 
  30.00–34.99       Equivocal 
  ≥35.00                 Antibody detected 

Results from any one IgM assay should not be used as a sole determinant of a current or recent infection. Because an IgM test can yield false positive results and low-level IgM antibody may persist for more than 12 months post-infection, reliance on a single test result could be misleading. Acute infection is best diagnosed by demonstrating the conversion of IgG from negative to positive. If an acute infection is suspected, consider obtaining a new specimen and submit for both IgG and IgM testing in two or more weeks.

  • Infectious Disease

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 1.5 mL serum 
  • Alternative: NA 
  • Minimum Volume: 0.7 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Room Temperature 
  • Specimen Stability
    • Room temperature: 4 days 
    • Refrigerated: 7 days 
    • Frozen: 30 days 
  • Reject Criteria
    • Gross hemolysis • Grossly lipemic • Grossly icteric 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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