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Quest Diagnostics

Encephalitis Antibody Evaluation with Reflex to Titer and Line Blot, Serum

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

Encephalitis Antibody Evaluation with Reflex to Titer and Line Blot, Serum - The Encephalitis Antibody Panel provides an evaluation of possible autoantibodies in patients with suspected autoimmune encephalitis, and optimizes the likelihood of detecting neuronal specific autoantibodies, whether present singly or occurring as multiple autoantibodies.


Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.


Initial test

  • Acetylcholine Receptor Ganglionic (Alpha 3) Antibody
  • AGNA/SOX1 Antibody, IFA
  • AMPAR1 Antibody, CBA
  • AMPAR2 Antibody, CBA
  • Amphiphysin Antibody, IFA
  • ANNA1 (HU) Antibody, IFA
  • ANNA2 (RI) Antibody, IFA
  • ANNA3 Antibody, IFA
  • Aquaporin-4 (NMO) Antibody, IFA
  • Aquaporin-4 Antibody (IgG), CBA, IFA
  • CASPR2 Antibody, CBA
  • CRMP5/CV2 Antibody, IFA
  • DPPX Receptor Antibody, CBA, IFA
  • GABAB Receptor Antibodies, CBA
  • Glutamic Acid Decarboxylase (GAD65) Antibodies, IFA
  • Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, CBA
  • Ma (Ma-2/Ta) Antibodies, IFA
  • Myelin Antibody, IFA
  • NMDAR1 Antibody, CBA
  • Purkinje Cell Cytoplasmic Type-Tr (DNER) Antibody, IFA
  • Purkinje Cell Cytoplasmic Type-1 (PCA1/YO) Antibody, IFA
  • Purkinje Cell Cytoplasmic Type-2 (PCA2) Antibody, IFA
  • Tissue IFA Observations
  • Voltage-Gated Calcium Channel (VGCC) Type N Antibody
  • Voltage-Gated Calcium Channel (VGCC) P/Q type binding Antibody
  • Voltage-Gated Potassium Channel (VGKC) Antibody

Possible reflex biomarkers

  • Glutamic Acid Decarboxylase 65 Antibody
  • PCA-Tr Ab, Serum, Line Blot [Units/Volume]
  • Zinc Finger Protein of the Cerebellum 4 Ab, Serum, Line Blot [Units/Volume]
  • Glial Nuclear Type 1 Ab, Serum, Line Blot [Units/Volume]
  • Amphiphysin Ab, Serum [Units/Volume]
  • CV2 Ab, Serum/Plasma [Units/Volume]
  • PCA-1 Ab, Serum, Immunoblot [Units/Volume]
  • Neuronal Nuclear Type 2 Ab, Serum [Units/Volume]
  • Neuronal Nuclear Type 1 Ab, Serum [Units/Volume]
  • Ma+Ta Ab, Serum, Line Blot [Presence]
  • Neuronal Nuclear Type 3 Ab, Serum [Titer]
  • Purkinje Cell Cytoplasmic Type-2 Ab, Serum, IFA [Titer]
  • Purkinje Cell Cytoplasmic Type-Tr Ab, Serum, CBIFA [Presence]
  • Purkinje Cell Cytoplasmic Type-Tr Ab, Serum, CBIFA [Titer]
  • Myelin Ab, Serum, IFA [Titer]
  • MAG/SGPG IgM Ab, Serum [Titer]
  • Myelin Associated Glycoprotein IgM, Serum [Titer]
  • NMDAR1 Ab, Serum, CBIFA [Titer]
  • AMPAR1 Ab, Serum, CBIFA [Titer]
  • AMPAR2 Ab, Serum, CBIFA [Titer]
  • GABABR Ab, Serum, CBIFA [Titer]
  • LGI1 Ab, Serum, CBIFA [Titer]
  • CASPR2 Ab, Serum, CBIFA [Titer]
  • DPPX Ab, Serum, CBIFA [Titer]
  • Aquaporin 4 Water Channel IgG, Serum, CBIFA [Titer]

Estimated days for results: Results should be available within 2 - 5 business days after samples are received at the lab.

Details

Encephalitis Antibody Evaluation with Reflex to Titer and Line Blot, Serum - The Encephalitis Antibody Panel provides an evaluation of possible autoantibodies in patients with suspected autoimmune encephalitis, and optimizes the likelihood of detecting neuronal specific autoantibodies, whether present singly or occurring as multiple autoantibodies.

Test Resources

2–5 business days


  • Autoimmune
  • Neurological

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations – enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 8 mL frozen serum 
  • Alternative: NA 
  • Minimum Volume: 4 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Refrigerated (Cold Packs) 
  • Specimen Stability: 
    • Room temperature: 24 hours 
    • Refrigerated: 14 days 
    • Frozen: 21 days 
  • Reject Criteria: 
    • Gross hemolysis • Grossly lipemic • Grossly icteric • Received room temperature • Received refrigerated • Freeze/thaw greater than 3 cycles • Turbid • Bacterial contamination 

State restrictions:

Patient can't order this test if they are located in Puerto Rico, Hawaii, Rhode Island, New Jersey, or New York

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