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Quest Diagnostics

Hepatic Function Panel

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

Hepatic Function Panel - This test is crucial for assessing liver injury, diagnosing liver diseases, and monitoring the treatment of liver diseases as well as the adverse effects of drugs that may harm the liver. It checks for levels of total protein, albumin, globulin, albumin/globulin ratio, total bilirubin, direct bilirubin, indirect bilirubin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).


  • Bilirubin (Indirect)
  • Direct Bilirubin
  • Albumin/Globulin Ratio
  • Total Bilirubin
  • Globulin (Calculated)
  • Alkaline Phosphatase (ALP)
  • Albumin
  • Aspartate Aminotransferase (AST)
  • Alanine Aminotransferase (ALT)
  • Protein, Total

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Hepatic Function Panel
This test is crucial for assessing liver injury, diagnosing liver diseases, and monitoring the treatment of liver diseases as well as the adverse effects of drugs that may harm the liver. It checks for levels of total protein, albumin, globulin, albumin/globulin ratio, total bilirubin, direct bilirubin, indirect bilirubin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).

ALT, AST, ALP, and bilirubin levels can indicate liver injury. ALT is more specific to the liver compared to AST. High levels of ALT and AST suggest liver cell injury, while high ALP and bilirubin levels suggest bile duct issues. High direct bilirubin levels can point to liver or bile duct problems. Albumin levels can show how well the liver is making proteins, which is a sign of its overall health.

This test is especially useful for people taking medications that might harm the liver, those with viral hepatitis, signs of chronic liver disease, risk factors for liver disease, or a family history of liver issues.

Understanding the results of each component can help in diagnosing specific liver conditions. Sometimes, further tests may be needed to clarify the results.

It's important to remember that liver enzymes show liver injury, not how well the liver is functioning. Tests like bilirubin, albumin, and prothrombin time can give a better picture of the liver's health.

Results should be viewed in the context of your overall health and history.

What type of sample is required for this test?
1 mL serum.


2–5 business days


  • Liver/Gallbladder

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 1 mL serum 
  • Alternative: NA 
  • Minimum Volume: 0.5 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Serum separator tube (SST) 
  • Transport Temperature: Room Temperature 
  • Specimen Stability
    • Room temperature: 24 hours 
    • Refrigerated: 72 hours 
  • Reject Criteria
    • Hemolysis • Received frozen 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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