
Hepatitis B Core Antibody, Total, with Reflex to IgM
Quest Diagnostics
Sample type: Serum
Requires fasting: No
Phlebotomy required
Details
Hepatitis B Core Antibody, Total, with Reflex to IgM - This assay detects presence of both IgG and IgM antibodies to the hepatitis B core (anti-HBc) antigen. If positive, it reflexes to further detect only the presence of IgM anti-HBc. When both the total anti-HBc and IgM anti-HBc are positive, it is indicative of acute HBV infection. A positive total anti-HBc with negative IgM anti-HBc is indicative of either acute or past Hepatitis B infection. Total anti-HBc may be the only HBV marker detected in past infection. Anti-HBc antibodies, both total and IgM, are absent from HBV vaccinated people.
Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.
Initial test
- Hepatitis B Core Antibody, Total
Possible reflex biomarkers
- Hepatitis B Core Antibody IgM
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
2–5 business days
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 1 mL serum
- Alternative: NA
- Minimum Volume: 0.8 mL
- Collection Instructions: NA
- Transport Container: Serum separator tube (SST)
- Transport Temperature: Room Temperature
- Specimen Stability:
- Room temperature: 5 days
- Refrigerated: 14 days
- Frozen: 21 days
- Reject Criteria:
- Gross hemolysis • Grossly lipemic
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island




