Hepatitis C Viral RNA, Quantitative Real-Time PCR with Reflexes
Quest Diagnostics
Sample type: Plasma
Requires fasting: No
Phlebotomy required
Details
Hepatitis C Viral RNA, Quantitative Real-Time PCR with Reflexes - Hepatitis C (HCV) viral genotype is required prior to the initiation of antiviral therapy with direct acting agents. In addition, the FDA package insert recommends baseline NS5a resistance testing for HCV genotype 1a patients being evaluated for treatment with Zepatier, which contains the NS5a inhibitor elbasvir and the NS3 protease inhibitor grazoprevir.
Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.
Initial test
- Hepatitis C Viral RNA, Quantitative, Real-Time PCR (Units/volume)
- Hepatitis C Viral RNA, Quantitative, Real-Time PCR (Log units/volume)
Possible reflex biomarkers
- Hepatitis C Virus Genotype
- HCV Genotype 1 NS5A Mutations
- Daclatasvir Susceptibility
- Ledipasvir Susceptibility
- Ombitasvir Susceptibility
- Elbasvir Susceptibility
- Velpatasvir Susceptibility
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
This reflex code offers clinicians the option to obtain the HCV Viral load, HCV genotype and NS5a resistance testing with a single test order when considering treatment with Zepatier or in other circumstances where all three tests are warranted.
2–5 business days
HCV RNA, QN, Real-Time PCR Not detected LogIUm/ML
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 3 mL plasma collected in an EDTA (lavender-top) tube
- Alternative: NA
- Minimum Volume: 1.8 mL
- Collection Instructions: NA
- Transport Container: Transport tube
- Transport Temperature: Refrigerated (Cold Packs)
- Specimen Stability:
- Room temperature: 72 hours
- Refrigerated: 14 days
- Frozen: 30 days
- Reject Criteria:
- Gross hemolysis • Grossly lipemic • Specimens collected using heparin as anticoagulant • Frozen whole blood
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
