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Quest Diagnostics

Itraconazole

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

The antifungal drug itraconazole is active in the treatment of aspergillosis, blastomycosis, histoplasmosis, sporotrichosis, and onychomycosis. It is a protein-bound drug and thus has negligible CSF penetration. It may also be utilized in the treatment of systemic candidiasis and cryptococcosis, especially when other drugs are contraindicated or ineffective. The chronic nature of fungal infections demands constant monitoring of itraconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted.


  • Itraconazole
  • Hydroxyitraconazole

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Details

Itraconazole - The antifungal drug itraconazole is active in the treatment of aspergillosis, blastomycosis, histoplasmosis, sporotrichosis, and onychomycosis. It is a protein-bound drug and thus has negligible CSF penetration. It may also be utilized in the treatment of systemic candidiasis and cryptococcosis, especially when other drugs are contraindicated or ineffective. The chronic nature of fungal infections demands constant monitoring of itraconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted

Test Resources

2–5 business days


Itraconazole (trough) localized infection            >0.50 mcg/mL
Itraconazole (trough) systemic infection            >1.00 mcg/mL

⁠⁠⁠⁠⁠⁠⁠The therapeutic window for the total of Itraconazole and its active metabolite, hydroxyl-itraconazole, is 1.00-4.00 mcg/mL.

  • Infectious Disease

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 2 mL serum collected in a red-top tube (no gel) 
  • Alternative: NA 
  • Minimum Volume: 1 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Refrigerated (Cold Packs) 
  • Specimen Stability
    • Room temperature: 72 hours 
    • Refrigerated: 14 days 
    • Frozen: 30 days 
  • Reject Criteria
    • Serum separator tubes (SST) • Other body fluid 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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