Juvenile Polyposis Panel (BMPR1A and SMAD4)
Quest Diagnostics
Sample type: Whole blood
Requires fasting: No
Phlebotomy required
Details
This test looks for specific genetic changes in the BMPR1A and SMAD4 genes that are linked to Juvenile Polyposis syndrome (JPS).
- Bmpr1a
- Smad4
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
Details
Juvenile Polyposis Panel (BMPR1A and SMAD4) - This test looks for specific genetic changes in the BMPR1A and SMAD4 genes that are linked to Juvenile Polyposis syndrome (JPS). People with JPS have a higher chance of developing colorectal cancer (40-50%) and stomach cancer (up to 21%, especially if they have many polyps in their stomach). They also have a slightly increased risk for cancers of the small intestine and pancreas. Identifying these genetic mutations can help manage and reduce the risk of cancer.
Who should consider this test?
This test is particularly important for individuals who have a family history of JPS or who have symptoms that could suggest JPS.
What type of sample is required for this test?
5 mL whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube. A simple blood draw is needed.
Test Resources https://education.questdiagnostics.com/faq/FAQ241
2–5 business days
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
Specimen
- Preferred Specimen(s): 5 mL whole blood collected in an EDTA (lavender-top) or ACD (yellow-top) tube
- Alternative: NA
- Minimum Volume: 2 mL
- Collection Instructions: NA
Storage and shipping instructions
- Transport Container: EDTA (lavender-top) tube
- Transport Temperature: Room Temperature
- Specimen Stability:
- Room temperature: 14 days
- Refrigerated: 14 days
- Reject Criteria: NA
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
