Lupus Anticoagulant Evaluation with Reflex
Quest Diagnostics
Sample type: Plasma
Requires fasting: No
Phlebotomy required
Details
Lupus Anticoagulant Evaluation with Reflex - Lupus anticoagulants (LA) are members of a family of antibodies with phospholipid-protein specificity. LA may be defined as an immunoglobulin, IgG or IgM or a mixture of both, that interferes with one or more of the in-vitro phospholipid (PL) dependent tests of coagulation. These antibodies are not associated with a hemorrhagic diathesis, but rather have been linked to thrombotic events. In addition to thrombosis other clinical complications have been associated with the presence of LA. These include strokes, nonbacterial thrombotic endocarditis, livedo reticularis and a variety of obstetrical complications such as intrauterine fetal death, recurrent spontaneous abortion, fetal growth retardation, early onset preeclampsia and chorea gravidarum.
Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.
Initial test
- Dilute Russell's Viper Venom Time (DRVVT) Screen
- Lupus Anticoagulant
- PTT-LA Screen
Possible reflex biomarkers
- Hexagonal Phase Confirmation
- Thrombin Clotting Time
- DRVVT Confirmation
- DRVVT 1:1 Mix
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
2–5 business days
PTT-LA Screen: ≤40 sec
dRVVT Screen: ≤45 sec
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 3 mL frozen, platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
- Alternative: NA
- Minimum Volume: 2 mL
- Collection Instructions: NA
- Transport Container: Transport tube
- Transport Temperature: Frozen
- Specimen Stability:
- Frozen: 30 days
- Reject Criteria:
- Hemolysis • Received thawed
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
