Lyme Disease Ab with Reflex to Blot (IgG, IgM)
Quest Diagnostics
Sample type: Serum
Requires fasting: No
Phlebotomy required
Details
Lyme Disease Ab with Reflex to Blot (IgG, IgM) - Lyme disease is caused by a bacterium borrelia burgdorferi and is transmitted by ticks. A screening test with high sensitivity is used as the first step in the CDC recommended algorithm. Immunoblot testing qualitatively examines, with high specificity, antibodies in a patient's specimen. Immunoblot testing is appropriate for confirming a detected screening result.
Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.
Initial test
- Lyme Antibody Screen
Possible reflex biomarkers
- 18 KD (IgG) Band
- 23 KD (IgG) Band
- 23 KD (IgM) Band
- 28 KD (IgG) Band
- 30 KD (IgG) Band
- 39 KD (IgG) Band
- 39 KD (IgM) Band
- 41 KD (IgG) Band
- 41 KD (IgM) Band
- 45 KD (IgG) Band
- 58 KD (IgG) Band
- 66 KD (IgG) Band
- 93 KD (IgG) Band
- Lyme Disease Antibodies (IgG), Immunoblot
- Lyme Disease Antibodies (IgM), Immunoblot
Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected
3–4 business days
<0.90 Negative
0.90–1.09 Equivocal
>1.09 Positive
As recommended by the Food and Drug Administration (FDA), all samples with positive or equivocal results in a Borrelia burgdorferi antibody screen will be tested using a blot method. Positive or equivocal screening test results should not be interpreted as truly positive until verified as such using a supplemental assay (e.g., B. burgdorferi blot).
The screening test and/or blot for B. burgdorferi antibodies may be falsely negative in early stages of Lyme disease, including the period when erythema migrans is apparent.
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 1 mL serum
- Alternative: NA
- Minimum Volume: 0.7 mL
- Collection Instructions: NA
- Transport Container: Transport tube
- Transport Temperature: Room Temperature
- Specimen Stability:
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
- Reject Criteria:
- Gross hemolysis • Grossly lipemic • Grossly icteric
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island
