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Quest Diagnostics

Neurology Antibody, CBA IFA

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

Neurology Antibody, CBA IFA - Detects specific neuronal antibodies to help evaluate autoimmune encephalitis and certain paraneoplastic neurological disorders.


  • AMPAR1 Antibody, CBA
  • AMPAR2 Antibody, CBA
  • CASPR2 Antibody, CBA
  • GABAB Receptor Antibodies, CBA
  • Leucine-Rich, Glioma-Inactivated Protein 1 Antibody, CBA
  • NMDAR1 Antibody, CBA

Estimated days for results: Results should be available within 2 - 5 business days after samples are received at the lab.

Details

Neurology Antibody, CBA IFA - Autoantibodies to brain neurotransmitter cell surface receptors may be seen in paraneoplastic syndromes or in idiopathic autoimmune encephalitis. Antibodies to N-methyl-D-aspartate receptor (NMDAR1) may be seen in a progressive syndrome leading to behavioral changes, psychosis, seizures and coma; teratoma or other neoplasms are seen in some cases. Antibodies to voltage gated potassium channel (VGKC) are found in paraneoplastic and idiopathic autoimmune encephalopathy; in many cases, antibodies actually target VGKC-associated proteins LGI-1 or CASPR2. Antibodies to AMPAR1 and AMPAR2 are usually associated with limbic encephalitis but can present with other symptoms or psychosis, and is paraneoplastic in >50% of cases.

Test Resources

2–5 business days


NMDAR1 Ab, CBA     Negative
AMPAR1 Ab, CBA      Negative
AMPAR2 Ab, CBA      Negative
GABABR Ab, CBA      Negative
LGI1 Ab, CBA              Negative
CASPR2 Ab, CBA       Negative

  • Autoimmune
  • Neurological

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations – enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 0.5 mL serum collected in a red-top tube (no gel) 
  • Alternative: NA 
  • Minimum Volume: 0.3 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Room Temperature 
  • Specimen Stability: 
    • Room temperature: 7 days 
    • Refrigerated: 14 days 
    • Frozen: 21 days 
  • Reject Criteria: 
    • Serum separator tube (SST) 

State restrictions:

Patient can't order this test if they are located in Puerto Rico, Hawaii, Rhode Island, New Jersey, or New York

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