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Quest Diagnostics

Phosphatidylserine/Prothrombin (PS/PT) Antibody (IgM)

Quest Diagnostics

Sample type: Plasma

Requires fasting: No

Phlebotomy required


Details

Phosphatidylserine/Prothrombin (PS/PT) Antibody (IgM) - This test measures IgM antibodies directed against a phosphatidylserine/prothrombin complex (PS/PT). These antibodies have been reported to have a high association with venous thrombosis and obstetric abnormalities, but not with arterial thrombosis. In addition, a very high degree of concordance between the concentration of aPS/PT and lupus anticoagulant activity has been demonstrated.


  • Phosphatidylserine/ Prothrombin Antibody (IgM)

Estimated days for results: Results should be available within 2 - 5 business days after samples are received at the lab.

Details

Phosphatidylserine/Prothrombin (PS/PT) Antibody (IgM) - Antiphospholipid Syndrome (APS) is an acquired autoimmune thrombophilia characterized by thrombosis (venous and/or arterial or microvascular) and/or pregnancy loss or morbidity in association with persistent positivity of a heterogenous group of autoantibodies known as anti-phospholipid antibodies (APL). The international laboratory consensus criteria for the diagnosis of APS includes a positive lupus anticoagulant and/or moderate to high positivity for IgG/IgM Cardiolipin and Beta-2-Glycoprotein I antibodies. Although not included in the criteria classification for APS diagnosis, antibodies directed against a phosphatidylserine/prothrombin complex (PS/PT) have been reported to have a high association with venous thrombosis and obstetric abnormalities, but not with arterial thrombosis. In addition, a very high degree of concordance between the concentration of aPS/PT and lupus anticoagulant activity has been demonstrated.

Test Resources

2–5 business days


≤30 U

  • Hematology
  • Autoimmune

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations – enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 1 mL platelet-poor plasma collected in a sodium citrate (light blue-top) tube 
  • Alternative: NA 
  • Minimum Volume: 0.5 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Room Temperature 
  • Specimen Stability: 
    • Room temperature: 7 days 
    • Refrigerated: 30 days 
    • Frozen: 30 days 
  • Reject Criteria: 
    • Gross hemolysis • Grossly lipemic 

State restrictions:

Patient can't order this test if they are located in Puerto Rico, Hawaii, Rhode Island, New Jersey, or New York

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