Plasma Renin Activity with Reflex to Aldosterone
Quest Diagnostics
Sample type: Plasma
Requires fasting: No
Phlebotomy required
Details
Plasma Renin Activity with Reflex to Aldosterone - A suppressed Plasma Renin Activity (PRA), ≤1 ng/mL/hr, will reflex to Aldosterone test. This test is to screen patients for Primary Aldosteronism (PA). PA is under-recognized and the most common cause of secondary hypertension. Patients with untreated PA are at a higher risk of cardiovascular, kidney and metabolic disease when compared to essential hypertensive patients.
Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.
Initial test
- Plasma Renin Activity, LC/MS/MS
Possible reflex biomarkers
- ALDO/PRA Ratio
- Aldosterone, LC/MS/MS
Estimated days for results: Results should be available within 2 - 5 business days after samples are received at the lab.
Plasma Renin Activity with Reflex to Aldosterone - A suppressed Plasma Renin Activity (PRA), ≤1 ng/mL/hr, will reflex to Aldosterone test. This test is to screen patients for Primary Aldosteronism (PA). PA is under-recognized and the most common cause of secondary hypertension. Patients with untreated PA are at a higher risk of cardiovascular, kidney and metabolic disease when compared to essential hypertensive patients.
2–5 business days
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 1.8 mL frozen plasma collected in an EDTA (lavender-top) tube
- Alternative: NA
- Minimum Volume: 0.8 mL
- Collection Instructions: NA
- Transport Container: Transport tube
- Transport Temperature: Frozen
- Specimen Stability:
- Room temperature: 24 hours
- Refrigerated: 24 hours
- Frozen: 28 days
- Reject Criteria:
- Moderate to gross hemolysis • Grossly lipemic • Received thawed • Plasma collected in a plasma separator tube (PST)
State restrictions:
Patient can't order this test if they are located in Puerto Rico, Hawaii, Rhode Island, New Jersey, or New York
