PrEP HBV Triple Screen Panel with Reflexes
Quest Diagnostics
Sample type: Serum
Requires fasting: No
Phlebotomy required
Details
PrEP HBV Triple Screen Panel with Reflexes - This panel consists of the three tests recommended by the Centers for Disease Control and Prevention for screening for hepatitis B infection: 1) hepatitis B surface antigen (HBsAg); 2) antibody to hepatitis B surface antigen (anti-HBs); 3) total antibody to hepatitis B core antigen (anti-HBc). Low positive HBsAg samples will be confirmed by a HBsAg neutralization test. Reactive total anti-HBc samples will reflex to an anti-HBc IgM test.
Reflex testing uses predefined clinical logic to automatically order one or more follow-up tests based on the initial test results. Reflex tests are performed automatically without the intervention of the ordering practitioner. They are conducted using the same sample your Patient already provided. If reflex tests are required, there will be additional charges.
Initial test
- Hepatitis B Core Antibody, Total
- Hepatitis B Surface Antibody Immunity, Quantitative
- Hepatitis B Surface Antigen
Possible reflex biomarkers
- Hepatitis B Surface Antigen, Serum/Plasma, Neutralization Test [Presence]
- Hepatitis B Core Antibody IgM
Estimated days for results: Results should be available within 2 - 5 business days after samples are received at the lab.
PrEP HBV Triple Screen Panel with Reflexes - This panel consists of the three tests recommended by the Centers for Disease Control and Prevention for screening for hepatitis B infection: 1) hepatitis B surface antigen (HBsAg); 2) antibody to hepatitis B surface antigen (anti-HBs); 3) total antibody to hepatitis B core antigen (anti-HBc). Low positive HBsAg samples will be confirmed by a HBsAg neutralization test. Reactive total anti-HBc samples will reflex to an anti-HBc IgM test.
This panel can be ordered for universal HBV screening in all adults, including pregnant persons and patients who are at increased risk of acquiring HBV. Current guidelines recommend that asymptomatic adults be screened at least once for HBV. Periodic, repeat testing using this panel can be performed for individuals with appropriate risk factors.
This assay may be performed as part of an overall screening regimen for patients considering or who are currently taking HIV PrEP. Please refer to the "Preexposure Prophylaxis for the Prevention of HIV Infection in the United States - 2021 Update Clinical Practice Guideline" for additional information.
Conners EE, Panagiotakopoulos L, Hofmeister MG, et al. Screening and Testing for Hepatitis B Virus Infection: CDC Recommendations - United States, 2023. MMWR Recomm Rep. 023;72:1-25.
2–5 business days
Non-Reactive
Non-Reactive
≥10 mIU/mL
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 4 mL serum
- Alternative: NA
- Minimum Volume: 3 mL
- Collection Instructions: NA
- Transport Container: Transport tube
- Transport Temperature: Room Temperature
- Specimen Stability:
- Room temperature: 5 days
- Refrigerated: 14 days
- Frozen: 21 days
- Reject Criteria:
- Gross hemolysis • Grossly lipemic
State restrictions:
Patient can't order this test if they are located in Puerto Rico, Hawaii, Rhode Island, New Jersey, or New York
