Protein C Activity
Quest Diagnostics
Sample type: Plasma
Requires fasting: No
Phlebotomy required
Details
Protein C Activity - Protein C (PC) deficiency may be congenital or acquired and is associated with venous thrombosis. Acquired PC deficiency may occur with vitamin K antagonists/deficiency, liver disease, malignancy, consumptive DIC, surgery, trauma, and hepatic immaturity of the newborn.
- Protein C, Activity
Estimated days for results: Results should be available within 2 - 5 business days after samples are received at the lab.
Protein C Activity - Protein C (PC) deficiency may be congenital or acquired and is associated with venous thrombosis. Acquired PC deficiency may occur with vitamin K antagonists/deficiency, liver disease, malignancy, consumptive DIC, surgery, trauma, and hepatic immaturity of the newborn.
Expected impact by therapeutic levels (potential interference depends upon drug concentration):
- Vitamin K antagonists (eg warfarin): decrease
- Heparin (UFH or LMWH): no effect to falsely increased activity levels at higher levels
- Dabigatran or Argatroban (Thrombin Inhibitors): may falsely increase activity
- Rivaroxaban, Apixaban, Edoxaban (Factor Xa Inhibitors): may falsely increase activity
2–5 business days
≥16 years 70-180 % normal
Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:
Quest Diagnostics Patient Service Centers (PSC)
- Location: Visit a nearby Quest Diagnostics Patient Service Center.
- Cost: $10 sample collection fee (paid during lab order checkout).
- Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
- Collection Instructions:
- Bring a valid ID.
- Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
- Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
- More Info: Quest Diagnostics blood draw guide
Getlabs Mobile Phlebotomy
- Location: Sample collection at your home or office.
- Cost: $85 sample collection fee (paid during lab order checkout).
- Availability: Available in most locations – enter your ZIP code during checkout to confirm.
- Scheduling: Schedule your appointment here through your Fullscript account.
- Collection Instructions:
- Have your digital or printed requisition form and valid ID ready.
- Your phlebotomist will contact you by phone to coordinate arrival.
- More Info: Getlabs blood draw guide
- Preferred Specimen(s): 1 mL frozen platelet-poor plasma collected in 3.2% sodium citrate (light blue-top) tube
- Alternative: NA
- Minimum Volume: 0.5 mL
- Collection Instructions: NA
- Transport Container: Transport tube
- Transport Temperature: Frozen
- Specimen Stability:
- Frozen: 14 days
- Reject Criteria:
- Gross hemolysis • Received thawed
State restrictions:
Patient can't order this test if they are located in Puerto Rico, Hawaii, Rhode Island, New Jersey, or New York
