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Quest Diagnostics

PSA, Free and Total

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

Elevated PSA levels can indicate both benign and malignant conditions of the prostate. For men aged 50 or older, combining PSA tests with digital rectal exams enhances early detection of prostate cancer. After complete tumor resection, PSA levels should drop to undetectable levels, but may increase again if the disease recurs or if residual disease is present. Therefore, monitoring PSA levels is beneficial in managing prostate cancer patients.


  • Prostate-specific antigen (PSA), % Free
  • Prostate-specific antigen (PSA), Free
  • Prostate-specific antigen (PSA), Total

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Details
PSA, Free and Total - This test is crucial for men over 50 with total PSA levels between 4.0 and 10.0 ng/mL, as it helps estimate the likelihood of prostate cancer. The % free PSA measurement can assist in deciding whether a biopsy is necessary, potentially avoiding unnecessary procedures.

Elevated PSA levels can indicate both benign and malignant conditions of the prostate. For men aged 50 or older, combining PSA tests with digital rectal exams enhances early detection of prostate cancer. After complete tumor resection, PSA levels should drop to undetectable levels, but may increase again if the disease recurs or if residual disease is present. Therefore, monitoring PSA levels is beneficial in managing prostate cancer patients.

Who should consider this test?
Men over 50, especially those with PSA levels between 4.0 and 10.0 ng/mL, or those undergoing prostate cancer treatment and monitoring.

What type of sample is required for this test?
2 mL frozen serum.


2–5 business days


PSA, Total
Male       ≤4.0 ng/mL
Female     Not established

PSA, Free  See Laboratory Report

PSA, % Free
Male       >25 % (calc)
Female     Not established


  • Tumor markers
  • Men's health

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 2 mL frozen serum 
  • Alternative: NA 
  • Minimum Volume: 0.6 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Frozen 
  • Specimen Stability
    • Room temperature: 72 hours 
    • Refrigerated: 72 hours 
    • Frozen: 5 months 
  • Reject Criteria: NA 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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