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Quest Diagnostics

Purkinje Cell Cytoplasmic Antibody Type Tr (DNER), CBA IFA

Quest Diagnostics

Sample type: Serum

Requires fasting: No

Phlebotomy required


Details

Purkinje Cell Cytoplasmic Antibody Type Tr (DNER), CBA IFA - Delta/notch-like epidermal growth factor-related receptor (DNER) is a central nervous system-specific ligand for the Notch receptors expressed by cerebellar Purkinje neurons, essential for the normal development of Purkinje cells and Bergmann glia. DNER is the target of PCA-Tr antibodies associated with paraneoplastic cerebellar degeneration (PCD) in patients with Hodgkin's lymphoma.


  • Purkinje Cell Cytoplasmic Type-Tr Ab, Serum [Presence]

Estimated days for results: Results should be available within 2 - 5 business days after samples are received at the lab.

Details

Purkinje Cell Cytoplasmic Antibody Type Tr (DNER), CBA IFA - Delta/notch-like epidermal growth factor-related receptor (DNER) is a central nervous system-specific ligand for the Notch receptors expressed by cerebellar Purkinje neurons, essential for the normal development of Purkinje cells and Bergmann glia. DNER is the target of PCA-Tr antibodies associated with paraneoplastic cerebellar degeneration (PCD) in patients with Hodgkin's lymphoma.

Test Resources

2–5 business days


Negative

  • Autoimmune
  • Neurological

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations – enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 0.5 mL serum collected in a red-top tube (no gel) 
  • Alternative: NA 
  • Minimum Volume: 0.3 mL 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: Transport tube 
  • Transport Temperature: Room Temperature 
  • Specimen Stability: 
    • Room temperature: 7 days 
    • Refrigerated: 14 days 
    • Frozen: 21 days 
  • Reject Criteria: 
    • Serum separator tube (SST) 

State restrictions:

Patient can't order this test if they are located in Puerto Rico, Hawaii, Rhode Island, New Jersey, or New York

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