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Quest Diagnostics

Total Glutathione in Whole Blood

Quest Diagnostics

Sample type: Whole blood

Requires fasting: No

Phlebotomy required


Details

Total Glutathione in Whole Blood - Glutathione is a tripeptide formed by a peptide linkage between the amine group of cysteine linked to glycine and the carboxyl group of the glutamate side-chain. It is an abundant cellular reducing agent, whose major biological function is mitigating oxidative damage to biological macromolecules. Glutathione is also important in the metabolism and excretion of xenobiotic compounds.


  • Total Glutathione

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Details
Total Glutathione in Whole Blood - Glutathione is a tripeptide formed by a peptide linkage between the amine group of cysteine linked to glycine and the carboxyl group of the glutamate side-chain. It is an abundant cellular reducing agent, whose major biological function is mitigating oxidative damage to biological macromolecules. Glutathione is also important in the metabolism and excretion of xenobiotic compounds. Glutathione is consumed to maintain cells in a reduced condition. Consequently, glutathione levels in patient samples are expected to be diminished in disease states where oxygen reactive species are involved, such as rheumatoid arthritis and atherosclerosis. Low glutathione levels have been linked to reduced dopamine production in neurons, which suggests a relationship to dopamine based neurological disorders such as parkinson's disease. High levels of glutathione have been linked to chemotherapy resistance in cancer treatments.

What type of sample is required for this test?
1 full tube of whole blood collected in an ACD solution B (yellow-top) tube

Test Resources
For more information, please consult your healthcare provider.


2–5 business days


373-838 uM

  • Oxidative stress

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

  • Location: Visit a nearby Quest Diagnostics Patient Service Center.
  • Cost: $10 sample collection fee (paid during lab order checkout).
  • Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
  • Collection Instructions:
    • Bring a valid ID.
    • Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.
  • Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
  • More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

  • Location: Sample collection at your home or office.
  • Cost: $85 sample collection fee (paid during lab order checkout).
  • Availability: Available in most locations enter your ZIP code during checkout to confirm.
  • Scheduling: Schedule your appointment here through your Fullscript account.
  • Collection Instructions:
    • Have your digital or printed requisition form and valid ID ready.
    • Your phlebotomist will contact you by phone to coordinate arrival.
  • More Info: Getlabs blood draw guide

 Specimen
  • Preferred Specimen(s): 1 full tube of whole blood collected in an ACD solution B (yellow-top) tube 
  • Alternative: NA 
  • Minimum Volume: NA 
  • Collection Instructions: NA 
 Storage and shipping instructions
  • Transport Container: ACD (yellow-top) tube 
  • Transport Temperature: Refrigerated (Cold Packs) 
  • Specimen Stability
    • Refrigerated: 21 days 
  • Reject Criteria
    • Hemolysis • Samples oversaturated with ACD solution 

State restrictions:

Patient can't order this test if they are located in Hawaii, Puerto Rico, New Jersey, New York, or Rhode Island

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