Vasoactive Intestinal Peptide (Plasma/GI Tube)

Quest Diagnostics

Sample type: Plasma

Requires fasting: Yes

Phlebotomy required

Details

Vasoactive Intestinal Peptide (Plasma/GI Tube) - Vasoactive intestinal polypeptide (VIP) is a 28 amino acid multifunctional peptide that is involved in gastrointestinal, vasodilator, and neuroendocrine functions.

Biomarker summary

Vasoactive Intestinal Peptide

Additional details

Estimated days for results: Results should be available in 2 - 5 business days after the sample is collected

Details

Vasoactive Intestinal Peptide (Plasma/GI Tube) - Vasoactive intestinal polypeptide (VIP) is a 28-amino acid multifunctional peptide that is involved in gastrointestinal, vasodilator, and neuroendocrine functions.

VIP is derived from larger pro-molecules that often exhibit the same or greater immunogenicity than the native VIP. It is structurally related to phim, glucagon, secretin, gastric inhibitory polypeptide, corticotropin-releasing factor, and growth hormone-releasing hormone. VIP stimulates pituitary release of prolactin, growth hormone, and ACTH. It stimulates luteinizing hormone-releasing hormone, serotonin, gastric somatostatin, steroids, and renin. VIP inhibits the release of gastrin, hypothalamic somatostatin, and histamine. VIP release is stimulated by cholinergic agonists, atropine, serotonin, prostaglandins e1 and d2, and nerve growth factor. VIP actions are inhibited by corticosteroids, dopamine, and opiate agonists. Elevated levels of VIP are found in patients with vipomas, hepatic cirrhosis, and Verner-Morrison's (watery diarrhea) syndrome. Decreased levels are found in cystic fibrosis.

What type of sample is required for this test?

1 mL plasma collected in an EDTA (lavender-top) tube

Test Resources

For more information, please consult your healthcare provider.

Average sample processing time

2–5 business days

Reference range

<36 pg/mL

Health categories

Patient instructions

Avoid taking any antacid medication or medications that affect intestinal motility for at least 48 hours prior to collection. Do not discontinue any prescription medications without first consulting with your doctor.

Fasting for 10-12 hours before your blood draw is required.

Fasting before a blood draw means you don't eat or drink anything except water.
Your doctor should provide any special instructions related to fasting for your test. Always follow your doctor's instructions.

Blood Draw Options with Fullscript
Fullscript offers several convenient phlebotomy options to complete your lab testing:

Quest Diagnostics Patient Service Centers (PSC)

Location: Visit a nearby Quest Diagnostics Patient Service Center.
Cost: $10 sample collection fee (paid during lab order checkout).
Scheduling: Schedule your appointment here. Appointments are recommended to reduce wait times. Walk-ins are accepted, but may experience delays. Aim to arrive 10 minutes before your appointment.
Collection Instructions:

Bring a valid ID.
Bring your digital or printed requisition form, available in the Labs tab of your Fullscript account.

Check-in: Scan the QR code from your confirmation email or follow kiosk instructions.
More Info: Quest Diagnostics blood draw guide

Getlabs Mobile Phlebotomy

Location: Sample collection at your home or office.
Cost: $85 sample collection fee (paid during lab order checkout).
Availability: Available in most locations – enter your ZIP code during checkout to confirm.
Scheduling: Schedule your appointment here through your Fullscript account.
Collection Instructions: