TruAge
TruDiagnostic
Sample type: Bloodspot
Requires fasting: Yes
At home test
Details
TruAge is an epigenetic test that assesses biological age, organ system aging, and pace of aging from a single blood sample. It combines three independently published epigenetic age clocks — OMICmAge™ (Harvard), SymphonyAge™ (Yale), and DunedinPACE™ (Duke) — to produce 14 unique age outputs across 11 mapped organ systems. Results are designed to support baseline assessment, care planning, and longitudinal monitoring alongside conventional labs.
- Average Telomere Length
- 1-Margaroyl-Glycerophospholipid GPE (17:0) (Epigenetic)
- 1-Stearoyl-2-Adrenoyl-GPC (18:0/22:4) (Epigenetic)
- 3-Ureidopropionate (Epigenetic)
- 4-Hydroxyphenylacetylglutamine (Epigenetic)
- 4-Methoxyphenol Sulfate (Epigenetic)
- Albumin (Epigenetic)
- Alcohol Consumption Risk
- Alkaline Phosphatase (Epigenetic)
- Androsterone Sulfate (Epigenetic)
- B Memory Cells % (Epigenetic)
- Basophils % (Epigenetic)
- Blood Urea Nitrogen (Epigenetic)
- Bone Morphogenetic Protein 1 (Epigenetic)
- C-Reactive Protein (Epigenetic)
- Carboxypeptidase B2 (Epigenetic)
- Carotene Diol (Epigenetic)
- CD4T / CD8T Ratio (Epigenetic)
- Creatinine (Epigenetic)
- DunedinPACE: Pace of Aging
- Eosinophils % (Epigenetic)
- Glucose (Epigenetic)
- Gluconate (Epigenetic)
- Hemoglobin A1c (Epigenetic)
- Hematocrit (Epigenetic)
- Hemoglobin (Epigenetic)
- Histone H2B Type 1-K (Epigenetic)
- Interleukin-6 (Epigenetic)
- Insulin-like Growth Factor-Binding Protein 2 (Epigenetic)
- Inter-Alpha-Trypsin Inhibitor Heavy Chain H3 (Epigenetic)
- Memory CD4T Cells % (Epigenetic)
- Memory CD8T Cells % (Epigenetic)
- Monocytes % (Epigenetic)
- N-Acetyl-Isoputreanine (Epigenetic)
- Naive B Cells % (Epigenetic)
- Naive CD4T Cells % (Epigenetic)
- Naive CD8T Cells % (Epigenetic)
- Natural Killer Cells % (Epigenetic)
- Neutrophil-to-Lymphocyte Ratio (Epigenetic)
- Neutrophils % (Epigenetic)
- OMICmAge: Biological Age
- Phenylacetylglutamine (Epigenetic)
- Red Blood Cell Distribution Width (Epigenetic)
- Regulatory T Cells % (Epigenetic)
- Ribitol (Epigenetic)
- Ribonuclease Pancreatic (Epigenetic)
- Serum Paraoxonase/Arylesterase 1 (PON1) (Epigenetic)
- Smoking Risk
- SYMPHONYAge: Blood Age
- SYMPHONYAge: Brain Age
- SYMPHONYAge: Heart Age
- SYMPHONYAge: Inflammation Age
- SYMPHONYAge: Kidney Age
- SYMPHONYAge: Liver Age
- SYMPHONYAge: Lung Age
- SYMPHONYAge: Metabolic Age
- SYMPHONYAge: Musculoskeletal Age
- Telomere Biological Age
- SYMPHONYAge: Hormone Age
- SYMPHONYAge: Immune Age
- Uridine (Epigenetic)
- Vanillactic Acid (Epigenetic)
- Versican Core Protein (Epigenetic)
Estimated days for results: Results should arrive 21 business days after the lab has received the sample.
TruAge is the only epigenetic assessment that combines three of the most extensively studied biological age clocks into a single multi-dimensional view of how a patient's body is aging. OMICmAge™, developed with Harvard University, functions as the odometer — a trackable measure of biological age versus chronological age that reflects accumulated biological wear. SymphonyAge™, developed by Yale University, acts as the organ-specific odometer, breaking aging down across 11 organ systems including brain, heart, immune, and metabolic. DunedinPACE™, developed by Duke University, is the speedometer, assessing how fast the body is aging right now; in a seven-year head-to-head study of 14 consensus aging biomarkers, it outperformed CRP, grip strength, and gait speed as a predictor of mortality.
TruAge is built on published, peer-reviewed algorithms rather than proprietary black-box scoring, and demonstrates an average ICC greater than 0.98 in independent validation — supporting high retest reliability and making it suitable for tracking change over time. DunedinPACE in particular is designed to assess pace of aging and supports monitoring over 3–6 month intervals.
In practice, TruAge is most useful when a provider needs to answer questions such as:
- What is this patient's biological age relative to chronological age?
- Which organ systems are aging faster than others?
- Is the current care plan moving the patient's biology in the right direction?
Recommended retesting cadence is every 3 months for patients on an active intervention or optimization protocol, every 6 months for ongoing monitoring, and annually for long-term maintenance.
Collection is a single blood sample, completed at home. For optimal interpretability, collect when the patient is in a stable health state; allow at least three weeks following acute illness, injury, or a major health event where possible.
TruAge is a wellness test intended to provide epigenetic and biological-aging insights that support provider-guided wellness planning, patient education, lifestyle-focused care, and longitudinal monitoring. It is not intended for use in the diagnosis of disease or other conditions, or in the cure, mitigation, treatment, or prevention of disease.
21 business days
Before You Start
- Read the test collection instructions provided in your kit.
- Continue taking your medications and supplements as normal.
- Avoid collecting your sample for at least three weeks following acute illness, injury, or a major health event.
Day Before Collection
- Hydrate for 24 hours before sample collection.
- Fast overnight before sample collection.
- Fasting means you don't eat or drink anything except water.
- Your doctor should provide any special instructions related to fasting for your test. Always follow your doctor's instructions.
Day of Collection
- Collect your sample upon waking.
Minimum age:
18
State restrictions:
Patient can't order this test if they are located in Hawaii, Puerto Rico, Rhode Island, New Jersey, or New York
