Public protocols

Cleveland Clinic: Omega-3 Fatty Acids Options

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Safety Interactions: Caution use with patients taking warfarin and other anticoagulant medications due to potential bleeding risk. (NIH: ODS 2025) (Merck Manual 2025) Recommend that daily intake not exceed 3 grams per day of EPA and DHA combined, with no more than 2 grams per day deriving from supplements. (NIH: ODS 2025) (Krupa & Fritz 2024) Caution use in patients taking tipranavir oral solution. (Aptivus prescribing information 2005) Conditions: Patients with established high-risk cardiovascular disease and elevated triglycerides have a higher incidence of atrial fibrillation, compared to placebo, when supplementing with omega 3 fatty acids. (Lombardi 2021) Following acute myocardial infarction (MI), patients taking omega 3 fatty acids may also be at an increased risk of atrial fibrillation. (Myhre 2023) Side Effects: Diarrhea, eructation, dermatitis, dyspepsia, nausea. (Chang 2023) (Merck Manual 2025) Halitosis, headache, and odoriferous sweat. (NIH: ODS 2025) (Krupa 2024)

Cleveland Clinic: Berberine Options

Cleveland Clinic: Urolithin A (UA)

Safety Interactions: No significant interactions reported; theoretical caution if using mitochondrial-targeting drugs. Conditions: Based on current research, there are no definitive contraindications for Urolithin A supplementation. Side Effects: No serious adverse effects (AE) attributed directly to UA reported in a systematic review of 5 RCTs. (Kuerec 2024)

Nutritional Support (Multivitamins/Minerals)

Cleveland Clinic: Turmeric/Curcumin Options

Cleveland Clinic: Vitamin B9 (Folate) Options

Cleveland Clinic: Vitamin D3 Options

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Cleveland Clinic: Nutritional Support (Electrolytes) Options

Cleveland Clinic: Sibo Options

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