Public protocols
18 of Dr. Exume's Dispensary's general recommendations, available to anyone who visits this store.
Liver Detoxification
2 more items in Liver DetoxificationLiver Detoxification Milk Thistle (Silybum marianum) 70-140mg, two to three times per day, minimum 12 weeks1 Compared to a controlled regimens, significant reduction of AST and ALT levels were observed1,2,3 Demonstrated decrease in transaminases of NASH patients, which led to a revival of liver function in NASH patients, hence improving prognosis and progression of liver cirrhosis1,2,3 US: Search for Milk Thistle in the Fullscript catalog. Vitamin E 800 IU, once per day, minimum 2 years4 Compared to control, vitamin E was shown to be effective in reducing fibrosis, AST, ALT, ALP, steatosis and inflammation5 It has been shown that vitamin E is the therapeutic choice for NASH as it has properties as an anti-inflammatory, anti-apoptotic and antioxidant6 US: Search for Vitamin E in the Fullscript catalog. Artichoke (Cynara scolymus) 600mg, once per day, minimum 2 months7 Artichoke leaf extract has been shown to have beneficial effects on liver enzymes ALT and AST7 Symptoms associated with NASH have been shown to be alleviated by artichoke leaf extract in addition to improving lipid levels and liver enzymes8 US: Search for Artichoke in the Fullscript catalog. Turmeric (Curcuma longa) 500-3000mg, total per day, minimum 8 weeks10,11,12,13 Curcumin has been shown to have protective effects through various mechanisms like PI3K/Akt and hepatic stellate cells activation, amelioration of the expression of Nrf2, SOD, CAT, GSH, GPx and GR, suppressing proinflammatory cytokines, lipid peroxidation products, PI3K/Akt and hepatic stellate cells activation9,13 Reduction in ALT, AST and GGT levels was observed10,11,12,13 US: Search for Curcuma longa in the Fullscript catalog. New and upcoming research: Reishi (Ganoderma lucidum) 225mg, total per day, minimum 6 months14 Ganoderma lucidum was shown to reverse mild fatty liver to a normal condition14 Reduction in GOT and GPT levels was observed14 US: Search for Ganoderma lucidum in the Fullscript catalog. References 1 (A) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728929/ 2 (B) - https://www.ncbi.nlm.nih.gov/pubmed/22343419/ 3 (B) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612568/ 4 (B) - https://www.ncbi.nlm.nih.gov/pubmed/20427778 5 (A) - https://www.ncbi.nlm.nih.gov/pubmed/26059365 6 (A) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313719/ 7 (B) - https://www.ncbi.nlm.nih.gov/pubmed/29520889 8 (B) - https://www.ncbi.nlm.nih.gov/pubmed/27735918 9 (A) - https://www.ncbi.nlm.nih.gov/pubmed/29966389 10 (B) - https://www.ncbi.nlm.nih.gov/pubmed/23497020 11 (B) - https://www.ncbi.nlm.nih.gov/pubmed/28158893 12 (C) - https://www.ncbi.nlm.nih.gov/pubmed/27270872 13 (C) - https://www.ncbi.nlm.nih.gov/pubmed/30345311 14 (C) - https://www.ncbi.nlm.nih.gov/pubmed/28183232
View protocolAdrenal Support
Adrenal Support Ashwaghanda (Withania somnifera) 300mg, total per day, minimum 8 weeks1,2 Serum cortisol, body weight, and body mass index, Perceived Stress Scale and Food Cravings Questionnaire, Oxford Happiness Questionnaire and Three-Factor Eating Questionnaire were all improved1,2 Ashwaghanda safely improved resistance to stress in individuals2 For a more detailed review of Withania somnifera, refer to the Fullscript reference sheet: https://fullscript.com/hcp/withania-somnifera-reference US: Search for Withania Somnifera in the Fullscript catalog. Rhodiola (Rhodiola rosea) 576mg, total per day, minimum 28 days3 Rhodiola increases mental performance including the capacity to concentrate and decreased cortisol response to awakening stress3 Improvement in general fatigue including aspects like physical and mental fatigue, neuro-motoric tests and overall wellbeing was shown to be significantly improved4,5 For a more detailed review of Rhodiola rosea, refer to the Fullscript reference sheet: https://fullscript.com/hcp/rhodiola-rosea-reference US: Search for Rhodiola rosea in the Fullscript catalog. Panax ginseng 960-2000mg, total per day, minimum 4 weeks7,8 Numerical Rating Scale (NRS) score was improved7 Panax has shown to reduce circulating cortisol while increasing enzymatic and nonspecific antioxidant activity in response to physical stress8 Dosing of 2000 mg per day improved the visual analogue scale (VAS) results7 Reactive oxygen species (ROS) and malondialdehyde (MDA) levels were lowered and a dosing of 1000 mg increased GSH concentration and activity7 US: Search for Panax Ginseng in the Fullscript catalog. References 1 (B) - https://www.ncbi.nlm.nih.gov/pubmed/27055824 2 (B) - https://www.ncbi.nlm.nih.gov/pubmed/23439798?dopt=Abstract 3 (B) - https://www.ncbi.nlm.nih.gov/pubmed/19016404 4 (B) - https://www.ncbi.nlm.nih.gov/pubmed/11081987 5 (C) - https://www.ncbi.nlm.nih.gov/pubmed/10839209 6 (A) - https://www.ncbi.nlm.nih.gov/pubmed/29624410 7 (B) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629193/ 8 (C) - https://www.ncbi.nlm.nih.gov/pubmed/28981384
View protocolMen's Health - Prostate Care
Men's Health - Prostate Care Saw Palmetto (Serenoa repens) 320-960mg, total per day, minimum 3 to 5.5 months1,2 Decrease in inflammatory markers that contribute to the evolution of chronic prostatic inflammation and subsequent hyperplasia1 Saw Palmetto supplementation resulted in an increase in average flow rate values, and decreases in prostate volume and IPSS score3 US: Search for Saw Palmetto in the Fullscript catalog. Lycopene 15mg, total per day, minimum 6 months4 Reduction in PSA levels and overall improvement of IPSS score5 Consistent lycopene supplementation has been shown to inhibit the overall progression of BPH5 US: Search for Lycopene in the Fullscript catalog. Beta-sitosterol 130mg, total per day, minimum 6 months6 Beta-sitosterol has been shown to improve IPSS score8 Overall improvement of quality of life (QOL), urinary and flow scores, which include maximum urinary flow and postvoid residual urine volume7,8 US: Search for Beta-sitosterol in the Fullscript catalog. Pygeum (Pygeum africanum) 100mg, total per day, minimum 2 months11 IPPS score and QOL were improved by 38% and 35% respectively11 A decrease of 19% in nocturia, 24% in residual urine volume and an increase of 23% in peak urine flow was observed10 Urologic symptoms and flow measures were improved9,10 US: Search for Pygeum africanum in the Fullscript catalog. References 1 (C) - https://www.ncbi.nlm.nih.gov/pubmed/26891611 2 (B) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5049653/ 3 (B) - https://www.ncbi.nlm.nih.gov/pubmed/28991765 4 (C) - https://www.ncbi.nlm.nih.gov/pubmed/18156403 5 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28440323 6 (B) - https://www.ncbi.nlm.nih.gov/pubmed/9313662 7 (A) - https://www.ncbi.nlm.nih.gov/pubmed/10368239 8 (B) - https://www.ncbi.nlm.nih.gov/pubmed/10792163 9 (A) - https://www.ncbi.nlm.nih.gov/pubmed/11099686 10 (A) - https://www.ncbi.nlm.nih.gov/pubmed/11869585 11 (B) - https://www.ncbi.nlm.nih.gov/pubmed/10475357
View protocolNeurological Health - Mood Support
Neurological Health - Mood Support St John’s Wort (Hypericum perforatum) 600mg, total per day of 0.3 % hypericin and 1-4 % hyperforin standardized formula, minimum 6 weeks2,4,5,6,7 Hypericum perforatum demonstrated similar efficacy to SSRIs including criteria like remission rate, Hamilton-Anxiety Scale and depressive symptoms in patients with mild to moderate depression1,2 Improvement in relapse rates, Hamilton-Anxiety Scale, Beck Depression Inventory time courses and greater over-all improvement (CGI) was observed. In addition, Hypericum perforatum demonstrated a potential for prophylactic effect in patients with chronic depression or depression alone5,6,7 Link to interaction white paper: Nutrient Interactions US: Search for Hypericum perforatum in the Fullscript catalog. Omega fatty acids 930-1400mg EPA 200-750mg DHA, total per day, minimum 12 weeks11,12 Dietary n-3 PUFA was shown to lower the risk of depression8,9,10 Higher levels of red blood cells EPA, DHA and ratio was correlated with improved remission rate12 US: Search for Omega fatty acids in the Fullscript catalog. Rhodiola (Rhodiola rosea) 340mg, total per day, minimum 6 weeks14,15 Cell response to stress was shown to be regulated by rhodiola, which in return, positively impacted overall mood13 Overall depression symptoms including insomnia, somatization and emotional instability were improved15 A decrease in the Hamilton-Anxiety Scale was observed with fewer adverse effects than sertraline14 US: Search for Rhodiola rosea in the Fullscript catalog. References 1 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28064110 2 (A) - https://www.ncbi.nlm.nih.gov/pubmed/27589952 3 (A) - https://www.ncbi.nlm.nih.gov/pubmed/19028540 4 (B) - https://www.ncbi.nlm.nih.gov/pubmed/22592504 5 (B) - https://www.ncbi.nlm.nih.gov/pubmed/21514125 6 (B) - https://www.ncbi.nlm.nih.gov/pubmed/20181361 7 (B) - https://www.ncbi.nlm.nih.gov/pubmed/18694635 8 (A) - https://www.ncbi.nlm.nih.gov/pubmed/21939614 9 (A) - https://www.ncbi.nlm.nih.gov/pubmed/27544316 10 (A) - https://www.ncbi.nlm.nih.gov/pubmed/26978738 11 (B) - https://www.ncbi.nlm.nih.gov/pubmed/28157380 12 (B) - https://www.ncbi.nlm.nih.gov/pubmed/26930527 13 (A) - https://www.ncbi.nlm.nih.gov/pubmed/27013349 14 (B) - https://www.ncbi.nlm.nih.gov/pubmed/25837277 15 (B) - https://www.ncbi.nlm.nih.gov/pubmed/17990195 16 (C) - https://www.ncbi.nlm.nih.gov/pubmed/30477830
View protocolWomen's Health - Ovarian Wellness (cysts)
Women's Health - Ovarian Wellness (cysts) Berberine 500 mg, three times per day, minimum 3 months Reductions in total testosterone, free androgen index, fasting glucose, fasting insulin and HOMA-IR, and increases in SHBG.1 Decreases in BMI, lipid parameters and total FSH requirement, and an increase in live birth rate with fewer gastrointestinal adverse events.1 Decrease the waist circumference and waist-to-hip ratio, total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol as well as increase in high-density lipoprotein cholesterol (HDLC) and sex hormone-binding globulin.2 Search for Berberine in the Fullscript catalog. D-Chiro-Inositol (DCI) 1 g, twice per day, minimum 6 months Improved the regularity of the menstrual cycle, the Acne Score, the endocrine and metabolic parameters and the insulin-resistance 3 Effective in improving ovarian function and metabolism in patients with PCOS, and reduced hyperandrogenism better 4 Search for D-Chiro-Inositol in the Fullscript catalog. Myo-Inositol 1 g, twice per day, minimum 6 months Significantly decreased serum total testosterone, modified Ferriman-Gallwey (mF-G) scores and serum high-sensitivity C-reactive protein (hs-CRP) levels5 Meta-analysis demonstrates that myo-inositol improves HOMA index and increases the E2 (estradiol) level6 Search for Myo-Inositol in the Fullscript catalog. Chromium Picolinate 200 ug, per day, minimum 8 weeks Demonstrated significant reductions in fasting plasma glucose, insulin levels, homeostatic model of assessment for insulin resistance, and a significant increase in quantitative insulin sensitivity check index 7 Significantly decreased serum triglycerides, VLDL and total cholesterol concentrations Contributes to increases in plasma total antioxidant capacity and a significant reduction in malondialdehyde values 7 Overall reduction in BMI and free testosterone concentration 8 Search for Chromium Picolinate in the Fullscript catalog. References 1 (B) - https://www.ncbi.nlm.nih.gov/pubmed/23869585 2 (B) - https://eje.bioscientifica.com/view/journals/eje/166/1/99.xml 3 (B) - https://www.ncbi.nlm.nih.gov/pubmed/25670222 4 (B) - https://www.ncbi.nlm.nih.gov/pubmed/24351072 5 (B) - https://www.ncbi.nlm.nih.gov/pubmed/28485095 6 (A) - https://www.ncbi.nlm.nih.gov/pubmed/29052180 7 (A) - https://www.ncbi.nlm.nih.gov/pubmed/29307112 8 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28595797
View protocolWomen's Health - Hot Flashes
Women's Health - Hot Flashes Vitamin E 400-800IU, total per day, minimum 4 weeks1,2 Severity score and frequency of hot flashes was significantly improved compared to placebo1,2 US: Search for Vitamin E in the Fullscript catalog. Isoflavones 50-120mg, total per day, minimum 12 weeks3,4 Hot flash frequency and intensity was shown to be decreased compared to placebo4,5 Supplementation for at least 48 weeks is required in order to obtain 80% of maximum effect6 US: Search for Isoflavones in the Fullscript catalog. Evening Primrose oil 1000mg, total per day, minimum 6 weeks7 Frequency and severity of hot flashes compared to placebo was significantly improved7 HFRDIS (Hot Flash Related Daily Interference Scale) was ameliorated especially regarding social activities, relations with others, and sexuality score7 US: Search for Evening Primrose oil in the Fullscript catalog. References 1 (B) - https://www.ncbi.nlm.nih.gov/pubmed/17664882 2 (B) - https://www.ncbi.nlm.nih.gov/pubmed/9469333 3 (A) - https://www.ncbi.nlm.nih.gov/pubmed/30475519 4 (B) - https://www.ncbi.nlm.nih.gov/pubmed/20025635 5 (A) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389700/ 6 (A) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386944/ 7 (B) - https://www.ncbi.nlm.nih.gov/pubmed/23625331 8 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28160855 9 (B) - https://www.ncbi.nlm.nih.gov/pubmed/25581426 10 (A) - https://www.ncbi.nlm.nih.gov/pubmed/26471215
View protocolThyroid Health
Thyroid Health Selenium 200 μg, total per day of selenomethionine, minimum 3 months1,2,3 A decrease between 20% and 63.6% in anti-TPO marker was observed,1,2,3,4 US: Search for Selenium in the Fullscript catalog. Vitamin D 2000 IU, total per day, minimum 6 months6,7,8 It has been demonstrated that low levels of serum 25-hydroxyvitamin D is related to thyroid auto-immune diseases like Hashimotos5 Vitamin D has been shown to decrease concentrations of thyroid peroxidase and thyroglobulin antibodies6,7,8 Vitamin D has been linked to a decrease in thyroid autoimmunity in Hashimoto’s thyroiditis treated with levothyroxine. The impact is more significant for thyroid peroxidase than thyroglobulin antibodies8 The combination of Simvastatin and vitamin D supplementation had a stronger effect in reducing concentrations of thyroid peroxidase and thyroglobulin antibodies then vitamin D supplementation alone6 US: Search for Vitamin D in the Fullscript catalog. New and upcoming research: Cordyceps sinensis 6 g, total per day, minimum 24 weeks9 Preliminary research shows that Cordyceps sinensis may balance the proportion between helper T cells and cytotoxic T cells9 In addition, Cordyceps sinensis may contribute to a significant decrease in anti-TPO antibodies in Hashimoto’s thyroiditis patients9 US: Search for Cordyceps sinensis in the Fullscript catalog. Cannabis It has been shown that recent marijuana users (used within last 30 days), have lower TSH and anti-thyroperoxidase antibodies levels10 References 1 (B) - https://www.ncbi.nlm.nih.gov/pubmed/25894865 2 (B) - https://www.ncbi.nlm.nih.gov/pubmed/28042649 3 (B) - https://www.ncbi.nlm.nih.gov/pubmed/17696828 4 (A) - https://www.ncbi.nlm.nih.gov/pubmed/27702392 5 (A) - https://www.ncbi.nlm.nih.gov/pubmed/25854833 6 (B) - https://www.ncbi.nlm.nih.gov/pubmed/29331793 7 (B) - https://www.ncbi.nlm.nih.gov/pubmed/26637501 8 (C) - https://www.ncbi.nlm.nih.gov/pubmed/28073128 9 (B) - https://www.ncbi.nlm.nih.gov/pubmed/?term=cordyceps+TPO 10 (B) - https://www.ncbi.nlm.nih.gov/pubmed/27799014
View protocolSleep Support
Melatonin 2.5 to 3mg, total per day, minimum three weeks1,2 Increase in sleep quality was observed without adverse effects1,2 During the withdrawal period of melatonin, carryover of the effect on sleep latency time was observed on the following night1 Improvement in sleep onset latency, sleep-wake patterns, and delayed sleep phase syndrome3 The lowest dosing of exogenous melatonin is recommended in order to mimic the natural physiological circadian rhythm of melatonin4 US: Search for Melatonin in the Fullscript catalog. Magnesium 320mg, total per day of magnesium citrate, minimum 7 weeks5 Improvement of PSQI score, which includes improvements in sleep quality, sleep onset latency, sleep duration, sleep disturbance, daytime dysfunction, and hypnotic drug scores5 In addition to improving PSQI score, magnesium reduced early morning awakenings6 US: Search for Magnesium in the Fullscript catalog. Valerian (Valeriana officinalis) 1060mg, total per day, minimum 4 weeks7 Improvement in sleep quality and overall effectiveness observed in clinical insomnia7,9 Reduction in sleep latency was observed in a concentrated extract of a 5.3:1 ratio8 US: Search for Valeriana officinalis in the Fullscript catalog. References 1 (C) - https://academic.oup.com/sleep/article/35/10/1395/2596070 2 (B) - https://www.ncbi.nlm.nih.gov/pubmed/24718775 3 (A) - https://www.ncbi.nlm.nih.gov/pubmed/28648359 4 (A) - https://www.ncbi.nlm.nih.gov/pubmed/24802882 5 (B) - https://www.ncbi.nlm.nih.gov/pubmed/21199787 6 (C) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703169/ 7 (B) - https://www.ncbi.nlm.nih.gov/pubmed/21775910 8 (C) - https://www.ncbi.nlm.nih.gov/pubmed/17486686 9 (A) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394901/
View protocol
Powered by Fullscript
Explore the entire wellness catalog
High-quality wellness products, ready to shop the moment you join.
Sign up for Dr. Exume's Dispensary's store2M+
Patients served
50k+
Products to shop
Up to 10%
Off when you sign up
