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Dr. Ronald Hoffman's general recommendations, available to anyone who visits this store.

Intelligent Medicine Detox Protocol
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One of the things that infuriates me as a health care practitioner is how the word “detox” has been co-opted by charlatans trying to sell you suspect products you’re supposed to introduce into your body through various orifices. This nonsense has unfortunately clouded some of the real things you can do to bolster your body’s ability to cleanse itself. Simply opting for healthier clean foods is a great first step, but studies show that as caloric restriction causes fat cells to shrink, they release stored toxins into the system. Research has demonstrated that these harmful chemicals can actually poison metabolic pathways, causing slowed metabolism. This may actually sabotage weight loss efforts, causing weight to plateau even in the face of stringent diet adherence. The supplements in my Detox protocol have been chosen carefully to mobilize toxin elimination, easing the “blahs” that sometimes compromise your dietary resolve and get in the way of permanent sustainable weight loss. Start with Reg’Activ Liver and Detox. It delivers the unique probiotic lactobacillus fermentum ME-3 which generates glutathione; It also supports the liver’s processing of toxins with milk thistle, n-acetylcysteine, and selenium. ( Take one, twice daily.) Augment the glutathione support afforded by ME-3 with NAC (N-acetylcysteine) , the most efficient precursor to the body’s glutathione synthesis. Protects the liver, and speeds processing of environmental chemicals. (Take one, twice daily.) One of the most comprehensive detoxification formulas in the supplement marketplace, featuring a proprietary combination of botanicals and nutrients, Liver Detox supplies all you need to facilitate the elimination of waste products and harmful metabolic byproducts. (Take one, twice daily.) A time-tested traditional accouterment to detoxification protocols, chlorophyll has demonstrated the ability to accelerate the mobilization of xenobiotics via its action on Phase 1 and Phase 2 pathways. (Take one, twice daily.) DIM plus CDG combines two powerhouse detoxifiers: DIM (diindolylmethane) is derived from cabbage family vegetables, and accelerates the breakdown of environmental chemicals as well as excess xenoestrogens. CDG (calcium d-glucarate) aids in glucuronidation, the process by which the liver “tags” harmful compounds and allows them to be excreted from the body. (Take one, twice daily.) Vitamin C is one of the body’s most potent detoxifiers, so adding Ester-C is an essential accompaniment to your program. (Take one, three times daily.)
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Intelligent Medicine Bone Health Protocol
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The process of keeping our bones healthy spans a broad range of medical and lifestyle issues—abysmal diets that weaken bones; worsening rates of physical activity among U.S. adults; increasing numbers of Americans who take acid-blocking drugs that cause malabsorption of critical bone-building minerals; or escalating inappropriate use of blood pressure meds and sedatives in the elderly, even opioid overprescribing, that cause falls. There are several plausible ways of forestalling, and even reversing, bone loss: Weight-bearing exercise, yoga, an anti-inflammatory diet, and the right combination of supplements. These are the supplements I have recommended to my patients and audience for years. Bone Health Protocol CORE supplements: The foundation for good bone health involves, not just bio-available calcium, but also co-factors like magnesium, boron and ipriflavone. These and others are combined in OsteoThera (take two, twice daily with food) . Additional vitamin K2 in MK-7 (take one daily) enhances OsteoThera’s bone-building effects . MK-7 should not be taken with Coumadin or metformin. Strontium is my favorite supplement for reversing bone loss—scores of my patients and listeners can testify to improvements in bone density with regular use (take two at bedtime, away from calcium) . Ostera harnesses the anti-inflammatory effects of hops to staunch inflammation which erodes bones (take one, twice daily) . New research reveals the bone-protective effects of olive leaf polyphenols, hence DaVinci Olivir (take one, twice daily).
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Intelligent Medicine Seasonal Allergy Protocol
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Most often when seasonal allergies strike, we reach for the Claritin or the Allegra, but you can save yourself a trip to the pharmacy with these natural allergy-busters. If possible, get a jump on allergies by starting supplementation early, before symptoms begin. With the right intervention, you can stop the allergic cascade before it gets out of control. Allergy Protocol CORE supplements: Xlear: Bacteria and fungi that colonize the nasal passage and hide in biofilms are recognized as foreign invaders; their presence triggers chronic hyper-activation of the cells lining the respiratory tract. Xylitol in Xlear nasal spray inhibits microbes and dissolves biofilms, resulting in clearance of mucus. (Spray in each nostril every 4-6 hours as needed.) NAC: In Europe, it’s a prescription medicine, used for reducing congestion and for thinning tenacious mucus. It’s also a precursor of glutathione, the body’s premier antioxidant. (Take one, twice daily.) Aller-All™ is a well-balanced blend of vitamins, minerals and botanicals. These nutrients are known for their ability to support the body’s balanced response to environmental and seasonal changes.* Aller-All™ combines quercetin, bromelain, and vitamin C to work together to support healthy respiratory structures and functions.* This combination is also known to support the body’s normal response to typical seasonal challenges.* Other ingredients, such as B vitamins, zinc, magnesium, and licorice root have been included to further support both the respiratory and immune systems.* (Take one tablet, three times daily.) Himalayan Tartary Buckwheat (HTB) is an ancient plant loaded with protective phytonutrients. HTB Rejuvenate is rich in bioflavonoids, which may help combat seasonal allergies. (Take two, once daily.) With its combination of isoquercitrin, vitamin C, bromelain, and bioflavonoids, Aller-C is a potent and effective combination formula designed to help maintain normal respiratory and sinus function.* (Take two, twice daily.)
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Intelligent Medicine Starter Kit
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Many of you in my Intelligent Medicine audience have been asking for a short list of the basic supplements that I take, and would recommend as a starting point for those looking to take control of their health. I tried to keep this simple. I asked myself: What are the essential elements of a basic program that everyone could benefit from? I’ve given this a lot of thought, and here’s my list: No regimen is complete without a great multi: Alpha Base without iron capsules (take two, twice daily) . Of course, fish oil is a must, with all its great attributes for inflammation, heart, and brain, and I really like Big Bold Health’s Omega-3 Rejuvenate (take two, once daily) . Then, PhytoBenefits , formerly PhytoGuard, a combination of essential phytonutrients that I personally designed (take one, twice daily) . Because of the primacy of the microbiome in determining overall health, I added my favorite probiotic, Dr. Ohhira’s (take one, twice daily) . With benefits ranging from boosting immune processes to lowering the risk of heart disease, vitamin C is an essential nutrient that our bodies cannot produce on their own. To help you maintain proper levels, I added Ester C (take one, twice daily) . A quarter of Americans are considered vitamin D deficient , while 40% (and that’s the low estimate!) have levels lower than ideal. For those with certain health concerns, those numbers can be even higher. With that in mind, I’ve included Vitamin D3 2000IU (take once daily) as a vital component of the Intelligent Medicine Starter Kit. You can’t go wrong with this combination of basic nutrients; it’s a foundation you can build on with other specialized supplements to address additional health concerns.
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Intelligent Medicine Brain Support Protocol
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Many of us wonder sometimes what’s going on with our brains, like when we can’t recall a name that should be totally familiar to us or forget why we went into the kitchen! These worries take on a little more weight as we grow older, because we do know that there’s a natural decline in short-term memory and learning ability with age – a slow, progressive decline. It has even earned a medical acronym: ARMI, for age-related memory impairment. The good news is that several nutrients and nutraceuticals have been shown to slow cognitive decline and enhance memory and mental performance. I have aggregated some of the best into my Brain Support Protocol. Brain Support Protocol CORE supplements: Neurothera (take one, twice daily) is a great combination product incorporating amino acids, as well as all the most scientifically-vetted nutraceuticals for brain support. The curcumin in Cogumin SCLP (take one, twice daily) crosses the blood-brain barrier. The B vitamins in Methyl-Action (take one, twice daily) lower homocysteine and boost brain metabolism. Phosphatidylserine (take one, twice daily) is a mainstay of memory formulas. DHA from fish oil is key to infant brain development in utero and continues to protect the brain as we age. Big Bold Health’s Omega-3 Rejuvenate is minimally-processed and sustainably-sourced from Alaska, with naturally-occuring pro-resolving mediators (PRMs) and vitamins A and D to support brain wellness and promote mental clarity.* (Take two, once daily) . Lithium is an alkali metal found in nearly all vertebrate tissue. Vital Nutrients’ lithium orotate supports healthy neurotransmitter activity*, enhances Vitamin B12 and folate transport in the brain*, and may support mental and behavioral health.* (Take one, once daily with food) . Brain Support Protocol BOOSTER supplements: Ubiquinol (take one, twice daily), acetyl-l-carnitine (take one, twice daily) , and nicotinamide riboside (take one, twice daily) are a trio of nutrients that support energy metabolism in the mitochondria of brain cells. My favorite source of nicotinamide riboside is Niacel 400 by Thorne.
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Intelligent Medicine Seasonal Immune Protocol
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The best medicine is preventive medicine to bolster our immune defenses. While the Intelligent Medicine Starter Kit provides a good foundation for health, those looking to safeguard their immune systems will benefit from additional focused supplementation. Over the years I have refined my list of top supplements offering the greatest boost for your immune system when it is most needed. My patients and listeners who have followed this regimen report remarkably few instances other than the mildest respiratory infections. Give it a shot! Immune Protocol CORE supplements: Kyolic Formula 103 (take one, twice daily), a product which harnesses the documented immune-boosting effects of Aged Garlic Extract along with potent co-factors. Immpower (take one, twice daily) is my go-to for immune support. Fueled by potent ingredient AHCC (Advanced Hexose Correlated Compound), its benefits are substantiated by extensive research. I use it daily myself, and I recommend it to patients. Viracid (take one, twice daily) which contains zinc and echinacea. Essential Formulas Reg’ Activ Immune & Vitality , a unique probiotic that delivers protective glutathione. Himalayan Tartary Buckwheat (HTB) is an ancient plant with powerful immune-restoring properties. Among its myriad benefits, HTB Rejuvenate helps to strengthen immune performance*. (Take two, once daily.) Immune Protocol BOOSTER supplements: Xlear Nasal Spray : Airborne pathogens, particulates, and allergens enter our bodies through the nose and mouth where they are then absorbed, which can create an immune reaction which leads to a cold or flu. Xylitol in Xlear retards the formation of biofilms which perpetuate sinus problems. I recommend it to my patients during cold, flu, and allergy season. Vitamin C (take one, twice daily) is a mainstay of immune defense, protecting cells from free radical damage and enhancing immune function. Maintaining adequate Vitamin D (take one, once daily) levels has been associated with stronger immune function. Transfer Factor (take one, twice daily) , a colostrum-derived product that boosts the vigilance of white blood cells, and olive leaf extract ( Olivir , take one, twice daily ) that is rich in oleuropein, a potent natural antiviral NAC (take one, 1-2 times daily with food) supports healthy mucosal lining in sinus and respiratory systems, and proper lung function.
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Intelligent Medicine Stress Protocol
Life is full of challenges; it seems like more and more we're faced with situations and circumstances that raise our stress levels. Thankfully, there are natural solutions for easing some of our internal tension. I've created a protocol of must-haves for you to keep on hand to support your mental health during the times life piles on extra difficulties. These selections are tailored for helping your body weather stress and anxiety, and easing your mind when you need it most. Ashwagandha: A known adaptogen, ashwagandha has been shown to rein in elevated cortisol. Preferably take 500 mg one or two at bedtime. (Take one to two daily, at bedtime.) MagSRT®: MagSRT® gently releases 500mg (per serving) of magnesium slowly into your body to maximize absorption and avoid digestive discomfort. Their unique formula combines magnesium with P5P (Pyridoxal-5-Phosphate), the active form of Vitamin B6, to support the manufacture of serotonin and dopamine in the brain. (Take 4 tablets, once per day.) (PEA)+ with Meriva® Curcumin: Palmitoylethanolamide targets the endocannabinoid system for relaxation. ( Take two capsules daily.)
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Intelligent Medicine Women's Midlife Health Protocol
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Women's health needs—especially during the menopause transition—have gone unmet for too long. From a lack of research to outdated or conflicting recommendations that simply treat the symptoms of perimenopause and menopause without addressing their causes, many women are left without solutions to weather this challenging time. To that end, I'm offering a suite of products specifically designed to support women's health during midlife. FemmenessencePRO PERI is the first natural product to demonstrate, in published clinical trials, statistically significant effects on hormones in perimenopausal women by supporting the body’s own production. It contains 25% Maca-GO and 75% another phenotype specifically for perimenopausal women to support hormone balance and reduce menopausal symptoms. (Take 1 capsule twice daily with 8-16oz. of water before or between meals.) FemmenessencePRO POST is the first natural product to demonstrate, in published clinical trials, statistically significant effects on hormones in postmenopausal women by supporting the body’s own production. Maca-GO® contains a specific phenotype formulation to support hormone balance and bone health in postmenopausal women. (Take 2 capsules twice daily with 8-12oz. of water before or between meals.) Collagen Plus combines the well-known benefits of collagen and nicotinamide riboside with a supporting cast of plant extracts that have been clinically studied to support beauty from within. This pleasant-tasting powder promotes the hydration, elasticity, and strength of the skin* while reducing fine lines and wrinkles, and lightening and brightening skin pigment* (Mix 1 scoop with at least 8-12 ounces of water daily) Bone Support Formula: is a comprehensive bone support product that includes Magnesium and trace minerals, as well as Vitamins C, D and K2 to aid in the synthesis and maintenance of healthy bone tissue.* (Take 4 capsules daily with food, preferably in divided doses.) DIM 200 Plus CDG Promotes healthy hormone metabolism by supporting your body’s normal detoxification processes.* (Take one capsule daily, with a meal.)
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Intelligent Medicine Sleep Protocol
Sleep difficulties are all too prevalent, and can have myriad negative effects on both your daily life and physical health. Still, many who suffer from troubled sleep are reluctant to rely on prescription sleep aids. To support those seeking a more natural approach to improved sleep, I’ve created the Intelligent Medicine Sleep Protocol. These selections are tailored for helping your body relax and establish a more regular sleep rhythm. Cortisol Manager: A known adaptogen, ashwagandha has been shown to rein in elevated cortisol. Preferably take 500 mg one or two at bedtime. (Take one to two daily, at bedtime.) Sleep Support: Combining a powerful blend of sleep-promoting botanicals along with L-Theanine and GABA (gamma-amino butyric acid), Sleep Support promotes relaxation and alleviates occasional sleeplessness. (Take two at bedtime.) Melatonin-SR: Formulated to deliver melatonin gradually over 6–8 hours to mimic natural secretion patterns, Melatonin-SR contains 2 mg of sustained-release melatonin per capsule to support normal, healthy sleep onset and maintenance. (Take one at bedtime.) MagSoothe™: A great-tasting, fast-acting powder that utilizes the power of highly bioavailable magnesium glycinate to support healthy, restful sleep. (Take one scoop daily.)
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