Public protocols

Neurological Health - Nervous Tension

+66 more items in Neurological Health - Nervous Tension

Neurological Health – Nervous Tension Nervous tension is one of the most prevalent mental health symptoms and may lead to significant impairment in both emotional and physical health. It not only impacts the quality of life of the patient, but evidence shows that it may also increase the risk of all-cause mortality. The development of this symptom can be multifactorial and may include commonly known factors such as traumatic experiences, as well as the involvement of inflammatory cytokines, genetic susceptibility, and nutrient deficiencies Omega-3 fatty acids 2,500 mg, total per day of 2,085 mg EPA and 348 mg DHA, minimum 12 weeks Administration of omega-3 polyunsaturated fatty acids (PUFAs) demonstrated a reduction in anxiety, particularly in those with a clinical diagnosis of the disorder. However, the positive effects were limited to those receiving a minimum dose of 2,000 mg per day Lipopolysaccharide (LPS)-induced interleukin 6 (IL-6) has been shown to be reduced by omega-3 fatty acid intake, suggesting an anti-inflammatory effect An inverse correlation was shown between plasma omega-3 fatty acid levels and anxiety levels with omega-3 supplementation, leading to a 20% decrease in symptoms of anxiety in study participants L-theanine 200-400 mg, once per day, minimum 4 weeks Supplementation with L-theanine increased alpha brain wave activity indicating a potential mechanism for its ability to induce a relaxed, but alert state L-theanine has been shown to reduce stress-induced blood pressure elevation L-theanine supplementation improved self-rated anxiety scores, using the State-Trait Anxiety Inventory (STAI) Ashwagandha ( Withania somnifera ) 240-600 mg, total per day of standardized extract containing between 35% and 1.5% of withanolides, respectively, for a minimum 8 weeks A statistically significant reduction in Hamilton-Anxiety scale scores and morning cortisol levels was demonstrated with the use of ashwagandha One proposed mechanism of action was the moderating effect of ashwagandha on the hypothalamic-pituitary-adrenal axis (HPA axis) response to stressors; however, further investigation was suggested A study assessed the intervention of psychotherapy treatment (PT) alone versus Naturopathic treatments, which included the use of ashwagandha as well as dietary counseling, breathing techniques for relaxation, and a multivitamin. Symptoms, including anxiety as rated with the Beck Anxiety Inventory, social functioning, overall quality of life, fatigue, and concentration showed further improvement in the Naturopathic treatment group compared to the group receiving only psychotherapy Ashwagandha was shown to reduce serum cortisol levels from baseline levels which was correlated with a reduction in scores on stress assessment scales Magnesium 300 mg, once per day, minimum 8 weeks Magnesium may act as a modulator for the HPA axis by reducing adrenocorticotropic hormone (ACTH) and cortisol, and may be an important factor in the stress response Stress exposure has been shown to increase renal excretion of magnesium In participants with both anxiety and low serum magnesium, supplementation led to a reduction in scores on the Depression Anxiety Stress Scales (DASS-42) with consistent results in as little as four weeks Vitamin D 50,000 IU vitamin D3, once per one or two weeks, minimum 12 weeks An increase in serum serotonin levels and a decrease in serum neopterin levels were shown in the study group treated with vitamin D, in addition to standard of care (SOC), compared to a group receiving only SOC; additionally, the vitamin D treated participants also saw a decrease in Generalized Anxiety Disorder (GAD) scores, while no changes were seen in the SOC group In women with type 2 diabetes, vitamin D supplementation decreased anxiety levels from moderate to mild on the Depression, Anxiety and Stress Scales (DASS- 21) questionnaire, over the course of the study Inflammatory markers TNF-α and CRP are both increased in diabetic patients with anxiety; vitamin D supplementation was shown to reduce hs-CRP levels and increase IL-10 concentrations In a population subset of vitamin D-deficient adolescent females experiencing anxiety associated with PMS, vitamin D repletion demonstrated decreases in anxiety and irritability scores References: https://fullscript.com/protocol/neurological-health-nervous-tension

Immune Support for Covid, Colds and Flu

+99 more items in Immune Support for Covid, Colds and Flu

Vitamin C 1 g, once per day in adults 3 to 4 g, once per day at the onset of the common cold symptoms for the cold’s duration in adults1 Reduces the duration of the common cold by approximately a half-day, or by 8% in adults Reduces time of confinement by approximately six hours and fever duration by approximately a half-day, relieves chest pain and chills by approximately eight hours Improves antimicrobial and natural killer (NK) cell activities, lymphocyte levels, chemotaxis, delayed T cell responses, sympathetic nervous response, and induces anti-reactive oxygen species activity For more information on the uses of Vitamin C in other conditions, please refer to the Vitamin C reference guide . Echinacea purpurea Prevention: 0.9 mL, three times per day (equivalent to 2400 mg of extract), minimum 4 months7 Acute: Up to 4.5 mL liquid extract (equivalent to 4000 mg), once per day at the first stage of cold development7 Reduces the relative risk of cold development by 10-58% Reduces days with symptoms by 26% (1.4 days) and symptom scores by 23% 52% fewer patients requiring concomitant use of aspirin, paracetamol, or ibuprofen Reduces the incidence of cumulative viral infections by 26% and recurring infections by 59%, including influenza virus and parainfluenza virus Increases associated counts for white blood cells, monocytes, neutrophils, and natural killer cells, and suppresses superoxide production in the later-phase of the cold by neutrophils Zinc 75-100 mg of elemental zinc as zinc acetate or zinc gluconate lozenges, once per day, within 24 hours of the onset of common cold symptoms, minimum 1 to 2 weeks cold Reduces cold duration by 33%, or by approximately 1.65 to 3 days in healthy adults colds Zinc acetate equivalently reduces the duration by 40% and zinc gluconate reduces the duration by 28%, while other sources indicate greater efficacy with zinc acetate in healthy adults Reduces the incidence of cold symptoms after 5-7 days in healthy adults Reduces the duration of muscle soreness by 54%, cough by 46%, voice hoarseness by 43%, nasal congestion by 37%, nasal discharge by 34%, scratchy throat by 33%, sneezing by 22%, and sore throat by 18% in healthy adults Reduces the incidence of common cold development, absence from school, and antibiotic use in children Improves anti-inflammatory and antioxidant profile via reductions in plasma interleukin-1 receptor antagonist (IL-1ra), intercellular adhesion molecule-1 (ICAM-1), TNF-ɑ, MDA, HAE, and 8-oHdG, and increases in IL-2 mRNA in mononuclear cells in healthy adults Probiotics Probiotics may reduce the incidence of colds with minor effects on prevention, as well as improve influenza vaccination efficacy for A/H1N1, A/H3N2, and B strains, but is dependent on strain and population. Cold -- 1 billion CFU of Lactobacillus paracasei 8700:2 (DSM 13434) & Lactobacillus plantarum HEAL 9 (DSM 15312), once per day for 3 months Reduces the incidence of developing more than one common cold episode and number of days with a cold Reduces total symptom scores & pharyngeal symptoms of cold Reduces B lymphocyte proliferation Influenza -- 10 billion CFU of Lactobacillus fermentum CECT5716, once per day for 2 weeks before influenza vaccination and two weeks after Reduces the incidence of influenza 5-months after vaccination compared to vaccine alone Increases natural killer cells, T-helper response, and IgA levels -- 10 billion CFU of Lactobacillus rhamnosus GG, twice per day for 4 weeks after influenza vaccination Increases seroprotection for the H3N2 strain during the supplementation period -- 500 mg of Saccharomyces cerevisiae (EpiCor®), once per day for 12 weeks Reduces the incidence of cold/flu symptoms with or without prior vaccination Reduces the duration of symptoms with prior vaccination References link: https://fullscript.com/protocol/cold-and-flu-support

Whole30 Elimination Diet Support